“Torsade de pointes” during amiodarone infusion in a cirrhotic woman with a prolonged QT interval

2009 ◽  
Vol 41 (7) ◽  
pp. 535-538 ◽  
Author(s):  
A. Di Micoli ◽  
A. Zambruni ◽  
E. Bracci ◽  
B. Benazzi ◽  
P. Zappoli ◽  
...  
2020 ◽  
Vol 8 ◽  
pp. 232470962094840
Author(s):  
B K Anupama ◽  
Soumya Adhikari ◽  
Debanik Chaudhuri

Recent reports have suggested an increased risk of QT prolongation and subsequent life-threatening ventricular arrhythmias, particularly torsade de pointes, in patients with coronavirus disease-2019 (COVID-19) treated with hydroxychloroquine and azithromycin. In this article, we report the case of a 75-year-old female with a baseline prolonged QT interval in whom the COVID-19 illness resulted in further remarkable QT prolongation (>700 ms), precipitating recurrent self-terminating episodes of torsade de pointes that necessitated temporary cardiac pacing. Despite the correction of hypoxemia and the absence of reversible factors, such as adverse medication effects, electrolyte derangements, and usage of hydroxychloroquine/azithromycin, the QT interval remained persistently prolonged compared with the baseline with subsequent degeneration into ventricular tachycardia and death. Thus, we highlight that COVID-19 illness itself can potentially lead to further prolongation of QT interval and unmask fatal ventricular arrhythmias in patients who have a prolonged QT and low repolarization reserve at baseline.


2015 ◽  
Vol 5 (2S) ◽  
pp. 21-25
Author(s):  
Flavio Cerrato ◽  
Angelo Bosio ◽  
Claudio Pascale

We report a case of a 88-year-old female, admitted to the hospital with tachycardia, chest pain and dyspnoea. ECG revelead a recent new-onset atrial fibrillation. A pharmacological cardioversion with amiodarone was performed, and restoration of sinus rhythm was obtained. Sotalol for rhythm control was administered. On the eighth day after the admission, she presented with severe dyspnoea and hypotension. An ECG revelead torsade de pointes, associated with prolonged QT interval. Several factors are involved in determining dyspnoea. ECG, although not specific, is an important instrument that supports clinicians in assessment of dyspnoea.


CHEST Journal ◽  
1997 ◽  
Vol 112 (2) ◽  
pp. 556-557 ◽  
Author(s):  
Mark S. Link ◽  
Caroline B. Foote ◽  
Stephen B. Sloan ◽  
Munther K. Homoud ◽  
Paul J. Wang ◽  
...  

Author(s):  
Ghariani Rania ◽  
Chrif Yosra ◽  
Samar Derbal ◽  
Rihab Laamouri ◽  
Fatma Ben Dahmene ◽  
...  

2008 ◽  
Vol 1 (1) ◽  
pp. 35-41 ◽  
Author(s):  
Amanda S. Y. Chan ◽  
Geoffrey K. Isbister ◽  
Carl M. J. Kirkpatrick ◽  
Stephen B. Duffull

2002 ◽  
Vol 62 (2) ◽  
pp. 580-584 ◽  
Author(s):  
Alberto Bettinelli ◽  
Camillo Tosetto ◽  
Giacomo Colussi ◽  
Ginaluca Tommasini ◽  
Alberto Edefonti ◽  
...  

1997 ◽  
Vol 30 (4) ◽  
pp. 337-339 ◽  
Author(s):  
Rohan Perera ◽  
Andreas Kraebber ◽  
Miles J. Schwartz

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