Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors

2018 ◽  
Vol 143 ◽  
pp. 1563-1577 ◽  
Author(s):  
Jeshma Kovvuri ◽  
Burri Nagaraju ◽  
V. Lakshma Nayak ◽  
Ravikumar Akunuri ◽  
M.P. Narasimha Rao ◽  
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Keyword(s):  
Dna Binding ◽  
Topoisomerase I ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Topoisomerase I Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals A new scaffold of topoisomerase I inhibitors: Design, synthesis and biological evaluation

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Vol 124 ◽  
pp. 326-339 ◽  
Author(s):  
Alberto Mazza ◽  
Egle M. Beccalli ◽  
Alessandro Contini ◽  
Aida Nelly Garcia-Argaez ◽  
Lisa Dalla Via ◽  
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Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Topoisomerase I Inhibitors ◽  
Synthesis And Biological Evaluation

scholarly journals Design, Synthesis, and Biological Evaluation of 14-Substituted Aromathecins as Topoisomerase I Inhibitors

2008 ◽  
Vol 51 (15) ◽  
pp. 4609-4619 ◽  
Author(s):  
Maris A. Cinelli ◽  
Andrew Morrell ◽  
Thomas S. Dexheimer ◽  
Evan S. Scher ◽  
Yves Pommier ◽  
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Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Topoisomerase I Inhibitors ◽  
Synthesis And Biological Evaluation

Synthesis and Biological Evaluation of 1,5-Naphthyridines as Topoisomerase I Inhibitors. A New Family of Antiproliferative Agents

2015 ◽  
Vol 14 (23) ◽  
pp. 2722-2728 ◽  
Author(s):  
Concepcion Alonso ◽  
Maria Fuertes ◽  
Maria Gonzalez ◽  
Alicia Rodriguez-Gascon ◽  
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Keyword(s):  
Topoisomerase I ◽  
Biological Evaluation ◽  
Antiproliferative Agents ◽  
Topoisomerase I Inhibitors ◽  
New Family ◽  
Synthesis And Biological Evaluation
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