Design, synthesis, and evaluation of a novel prodrug, a S-trityl--cysteine derivative targeting kinesin spindle protein

Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors

10.1016/j.bmc.2019.115126 ◽

2019 ◽

Vol 27 (23) ◽

pp. 115126 ◽

Cited By ~ 2

Author(s):

Haytham O. Tawfik ◽

Tarek F. El-Moselhy ◽

Nabaweya S. El-Din ◽

Mervat H. El-Hamamsy

Keyword(s):

Protein Inhibitors ◽

Design Synthesis ◽

Design, synthesis, and molecular docking study of new monastrol analogues as kinesin spindle protein inhibitors

Archiv der Pharmazie ◽

10.1002/ardp.202000060 ◽

2020 ◽

Vol 353 (8) ◽

pp. 2000060

Author(s):

Mervat H. El‐Hamamsy ◽

Nabaweya A. Sharafeldin ◽

Tarek F. El‐Moselhy ◽

Haytham O. Tawfik

Keyword(s):

Molecular Docking ◽

Docking Study ◽

Protein Inhibitors ◽

Molecular Docking Study ◽

Design Synthesis ◽

Kinesin Spindle Protein (KSP) Inhibitors. Part 2. The Design, Synthesis, and Characterization of 2,4-Diaryl-2,5-dihydropyrrole Inhibitors of the Mitotic Kinesin KSP.

ChemInform ◽

10.1002/chin.200628111 ◽

2006 ◽

Vol 37 (28) ◽

Author(s):

Mark E. Fraley ◽

et al. et al.

Keyword(s):

Synthesis And Characterization ◽

Design Synthesis ◽

Kinesin Spindle Protein ◽

Ksp Inhibitors

De novo design, synthesis and biological evaluation of 1,4-dihydroquinolin-4-ones and 1,2,3,4-tetrahydroquinazolin-4-ones as potent kinesin spindle protein (KSP) inhibitors

Synthesis And Biological Evaluation

10.1016/j.bmc.2011.07.029 ◽

2011 ◽

Vol 19 (18) ◽

pp. 5612-5627 ◽

Cited By ~ 17

Author(s):

Cheng Jiang ◽

Lei Yang ◽

Wu-Tong Wu ◽

Qing-Long Guo ◽

Qi-Dong You

Keyword(s):

De Novo ◽

De Novo Design ◽

Biological Evaluation ◽

Design Synthesis ◽

Kinesin Spindle Protein ◽

Ksp Inhibitors ◽

ChemInform Abstract: Design, Synthesis and Evaluation of Tetrahydroisoquinolines as New Kinesin Spindle Protein Inhibitors.

ChemInform ◽

10.1002/chin.200947120 ◽

2009 ◽

Vol 40 (47) ◽

Author(s):

Cheng Jiang ◽

Qidong You ◽

Fei Liu ◽

Wutong Wu ◽

Qinglong Guo ◽

...

Keyword(s):

Protein Inhibitors ◽

Design Synthesis ◽

Design, Synthesis and Evaluation of Tetrahydroisoquinolines as New Kinesin Spindle Protein Inhibitors

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.57.567 ◽

2009 ◽

Vol 57 (6) ◽

pp. 567-571 ◽

Cited By ~ 7

Author(s):

Cheng Jiang ◽

Qidong You ◽

Fei Liu ◽

Wutong Wu ◽

Qinglong Guo ◽

...

Keyword(s):

Protein Inhibitors ◽

Design Synthesis ◽

Kinesin spindle protein (KSP) inhibitors. Part 2: The design, synthesis, and characterization of 2,4-diaryl-2,5-dihydropyrrole inhibitors of the mitotic kinesin KSP

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.01.030 ◽

2006 ◽

Vol 16 (7) ◽

pp. 1775-1779 ◽

Cited By ~ 53

Author(s):

Mark E. Fraley ◽

Robert M. Garbaccio ◽

Kenneth L. Arrington ◽

William F. Hoffman ◽

Edward S. Tasber ◽

...

Keyword(s):

Synthesis And Characterization ◽

Design Synthesis ◽

Kinesin Spindle Protein ◽

Ksp Inhibitors

Corrigendum to “Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors” [Bioorg. Med. Chem. 27 (2019) 115126]

10.1016/j.bmc.2019.115255 ◽

2020 ◽

Vol 28 (2) ◽

pp. 115255

Author(s):

Haytham O. Tawfik ◽

Tarek F. El-Moselhy ◽

Nabaweya S. El-Din ◽

Mervat H. El-Hamamsy

Keyword(s):

Protein Inhibitors ◽

Design Synthesis ◽

Corrigendum to “Design, synthesis, and bioactivity of dihydropyrimidine derivatives as kinesin spindle protein inhibitors” [Bioorg. Med. Chem. 27 (2019) 115126]

10.1016/j.bmc.2020.115687 ◽

2020 ◽

Vol 28 (19) ◽

pp. 115687

Author(s):

Haytham O. Tawfik ◽

Tarek F. El-Moselhy ◽

Nabaweya S. El-Din ◽

Mervat H. El-Hamamsy

Keyword(s):

Protein Inhibitors ◽

Design Synthesis ◽

Design, synthesis, SAR study, and biological investigation of novel N-substituted benzamide enaminones as potential anticonvulsant agents

10.1021/scimeetings.0c07052 ◽

2020 ◽

Author(s):

Patrice Ayotunde ◽

Yayin Fang ◽

Isis J Amaye ◽

Miguel Martin

Keyword(s):

Biological Investigation ◽

Design Synthesis ◽

Anticonvulsant Agents ◽

Substituted Benzamide ◽

Sar Study