Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.05.005 ◽

2013 ◽

Vol 65 ◽

pp. 436-447 ◽

Author(s):

Pillaiyar Thanigaimalai ◽

Sho Konno ◽

Takehito Yamamoto ◽

Yuji Koiwai ◽

Akihiro Taguchi ◽

...

Keyword(s):

Protease Inhibitors ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

3Cl Protease ◽

Synthesis And Biological Evaluation

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Design, synthesis, biological evaluation, structure-activity relationship study, and mode of action of 2-phenol-4,6-dichlorophenyl-pyridines

Bioorganic Chemistry ◽

10.1016/j.bioorg.2018.03.033 ◽

2018 ◽

Vol 79 ◽

pp. 1-18 ◽

Author(s):

Aarajana Shrestha ◽

Seojeong Park ◽

Somin Shin ◽

Tara Man Kadayat ◽

Ganesh Bist ◽

...

Keyword(s):

Mode Of Action ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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A Rational Design, Synthesis, Biological Evaluation and Structure–Activity Relationship Study of Novel Inhibitors against Cyanobacterial Fructose-1,6-bisphosphate Aldolase

Journal of Chemical Information and Modeling ◽

10.1021/acs.jcim.5b00618 ◽

2015 ◽

Vol 56 (1) ◽

pp. 73-81 ◽

Author(s):

Xinya Han ◽

Xiuyun Zhu ◽

Shuaihua Zhu ◽

Lin Wei ◽

Zongqin Hong ◽

...

Keyword(s):

Rational Design ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

Fructose 1,6 Bisphosphate

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Structure–Activity Relationship Study and Biological Evaluation of 2-(Disubstituted phenyl)-indole-5-propanoic Acid Derivatives as GPR40 Full Agonists

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c00031 ◽

2021 ◽

Vol 64 (7) ◽

pp. 4130-4149

Author(s):

Xiaodi Zhao ◽

Dong-Oh Yoon ◽

Jaeho Yoo ◽

Hyun-Ju Park

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Propanoic Acid ◽

Structure Activity ◽

Relationship Study

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Structure–activity relationship study at the 3′-N-position of paclitaxel: synthesis and biological evaluation of 3′-N-acyl-paclitaxel analogues

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(02)00218-3 ◽

2002 ◽

Vol 10 (10) ◽

pp. 3145-3151 ◽

Author(s):

E Roh

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Synthesis And Biological Evaluation

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Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo(1,4)oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.45.1975 ◽

1997 ◽

Vol 45 (12) ◽

pp. 1975-1983 ◽

Author(s):

Takeshi YAMAMOTO ◽

Manabu HORI ◽

Ikuo WATANABE ◽

Hisayoshi TSUTSUI ◽

Kengo HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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Potent and orally bioavailable CDK8 inhibitors: Design, synthesis, structure-activity relationship analysis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113248 ◽

2021 ◽

Vol 214 ◽

pp. 113248

Author(s):

Mingfeng Yu ◽

Theodosia Teo ◽

Yuchao Yang ◽

Manjun Li ◽

Yi Long ◽

...

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity ◽

Orally Bioavailable

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Design, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular Agents

American Journal of Infectious Diseases ◽

10.3844/ajidsp.2011.61.66 ◽

2011 ◽

Vol 7 (3) ◽

pp. 61-66 ◽

Author(s):

Rozita

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Biological Screening ◽

Design Synthesis ◽

Structure Activity ◽

Substituted Pyridines ◽

Relationship Study

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Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112866 ◽

2021 ◽

Vol 209 ◽

pp. 112866

Author(s):

Md Ashraf-Uz-Zaman ◽

Sadisna Shahi ◽

Racheal Akwii ◽

Md Sanaullah Sajib ◽

Mohammad Jodeiri Farshbaf ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

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Design, synthesis, and structure–activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.10.061 ◽

2010 ◽

Vol 20 (24) ◽

pp. 7327-7330 ◽

Author(s):

Elizabeth M. Moir ◽

Kazuya Yoshiizumi ◽

Jim Cairns ◽

Phillip Cowley ◽

Morag Ferguson ◽

...

Keyword(s):

Structure Activity Relationship ◽

Cb1 Receptor ◽

Activity Relationship ◽

Cannabinoid Cb1 Receptor ◽

Design Synthesis ◽

Receptor Agonists ◽

Structure Activity ◽

Relationship Study

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