Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112866 ◽

2021 ◽

Vol 209 ◽

pp. 112866

Author(s):

Md Ashraf-Uz-Zaman ◽

Sadisna Shahi ◽

Racheal Akwii ◽

Md Sanaullah Sajib ◽

Mohammad Jodeiri Farshbaf ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

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Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.08.067 ◽

2017 ◽

Vol 140 ◽

pp. 155-171 ◽

Author(s):

Dahong Yao ◽

Yuxin Zhou ◽

Lingjuan Zhu ◽

Liang Ouyang ◽

Jin Zhang ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Pyrimidine Moiety

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Design, Synthesis, and Structure–Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b00270 ◽

2015 ◽

Vol 58 (9) ◽

pp. 3957-3974 ◽

Author(s):

Chun-Hui Zhang ◽

Ming-Wu Zheng ◽

Ya-Ping Li ◽

Xing-Dong Lin ◽

Mei Huang ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

New Class ◽

Structure Activity

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Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.06.004 ◽

2019 ◽

Vol 178 ◽

pp. 589-605 ◽

Author(s):

Gang Liu ◽

Tao Yin ◽

Hyejin Kim ◽

Chunyong Ding ◽

Zhuo Yu ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

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Synthesis and structure-activity relationship studies of parthenolide derivatives as potential anti-triple negative breast cancer agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.01.058 ◽

2019 ◽

Vol 166 ◽

pp. 445-469 ◽

Author(s):

Weizhi Ge ◽

Xin Hao ◽

Fangzhi Han ◽

Zhongquan Liu ◽

Tianpeng Wang ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity

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Abstract 4204: Structure-activity relationship of diphenylamine derivatives to target epithelial to mesenchymal transition in triple negative breast cancer

10.1158/1538-7445.am2018-4204 ◽

2018 ◽

Author(s):

Akshita B. Bhatt ◽

Thomas D. Wright ◽

Katie Anna ◽

Mohit Gupta ◽

Patrick Flaherty ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Epithelial To Mesenchymal Transition ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Mesenchymal Transition ◽

Structure Activity ◽

Relationship Of

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Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo(1,4)oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.45.1975 ◽

1997 ◽

Vol 45 (12) ◽

pp. 1975-1983 ◽

Author(s):

Takeshi YAMAMOTO ◽

Manabu HORI ◽

Ikuo WATANABE ◽

Hisayoshi TSUTSUI ◽

Kengo HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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Design, Synthesis, Biological Screening and Structure Activity Relationship Study of 4, 6-Dimethyl-2-(Substituted) Mercapto-3-(Substituted) Pyridines as Anti Tubercular Agents

American Journal of Infectious Diseases ◽

10.3844/ajidsp.2011.61.66 ◽

2011 ◽

Vol 7 (3) ◽

pp. 61-66 ◽

Author(s):

Rozita

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Biological Screening ◽

Design Synthesis ◽

Structure Activity ◽

Substituted Pyridines ◽

Relationship Study

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Design, synthesis, and structure–activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.10.061 ◽

2010 ◽

Vol 20 (24) ◽

pp. 7327-7330 ◽

Author(s):

Elizabeth M. Moir ◽

Kazuya Yoshiizumi ◽

Jim Cairns ◽

Phillip Cowley ◽

Morag Ferguson ◽

...

Keyword(s):

Structure Activity Relationship ◽

Cb1 Receptor ◽

Activity Relationship ◽

Cannabinoid Cb1 Receptor ◽

Design Synthesis ◽

Receptor Agonists ◽

Structure Activity ◽

Relationship Study

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ChemInform Abstract: Design, Synthesis and Quantitative Structure-Activity Relationship Study of N-(3-Oxo-3,4-dihydro-2H-benzo[1,4]oxazine-7-carbonyl)guanidine Derivatives as Potent Na/H Exchange Inhibitors.

10.1002/chin.199823160 ◽

2010 ◽

Vol 29 (23) ◽

pp. no-no

Author(s):

T. YAMAMOTO ◽

M. HORI ◽

I. WATANABE ◽

H. TSUTSUI ◽

K. HARADA ◽

...

Keyword(s):

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Guanidine Derivatives ◽

Structure Activity ◽

Relationship Study

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