Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113821 ◽

2021 ◽

pp. 113821

Author(s):

Xiu-Xiu Wang ◽

Fei Xie ◽

Cong-Cong Jia ◽

Ning Yan ◽

Yan-Li Zeng ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Histone Deacetylase ◽

Biological Evaluation ◽

Histone Deacetylase 6 ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Phthalimide‐(N‐alkylbenzylamine) cysteamide hybrids as multifunctional agents against Alzheimer’s disease: Design, synthesis and biological evaluation

Chemical Biology & Drug Design ◽

10.1111/cbdd.13905 ◽

2021 ◽

Author(s):

Heng Zhang ◽

Qing Song ◽

Guangjun Yu ◽

Zhongcheng Cao ◽

Xiaoming Qiang ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Semi-synthesis and biological evaluation of flavone hybrids as multifunctional agents for the potential treatment of Alzheimer's disease

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.103917 ◽

2020 ◽

Vol 100 ◽

pp. 103917

Author(s):

Shaochun Shi ◽

Huibin Wang ◽

Jian Wang ◽

Yvxi Wang ◽

Xiaobian Xue ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Potential Treatment ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112193 ◽

2020 ◽

Vol 192 ◽

pp. 112193 ◽

Cited By ~ 3

Author(s):

Hui-Ju Tseng ◽

Mei-Hsiang Lin ◽

Young-Ji Shiao ◽

Ying-Chen Yang ◽

Jung-Chun Chu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Biological Evaluation ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of benzylisoquinoline derivatives as multifunctional agents against Alzheimer’s disease

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2014.03.058 ◽

2014 ◽

Vol 24 (10) ◽

pp. 2368-2373 ◽

Cited By ~ 5

Author(s):

Zi-Chen Xu ◽

Xiao-Bing Wang ◽

Wen-Ying Yu ◽

Sai-Sai Xie ◽

Su-Yi Li ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of 2-acetyl-5- O -(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer’s disease

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2017.09.057 ◽

2017 ◽

Vol 27 (22) ◽

pp. 5046-5052 ◽

Cited By ~ 9

Author(s):

Zhipei Sang ◽

Keren Wang ◽

Huifang Wang ◽

Huijuan Wang ◽

Qianwen Ma ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Alkyl Phenol ◽

Phenol Derivatives ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of Schiff’s base derivatives as multifunctional agents for the treatment of Alzheimer’s disease

Medicinal Chemistry Research ◽

10.1007/s00044-020-02666-6 ◽

2020 ◽

Author(s):

Jian Shi ◽

Yi Zhou ◽

Keren Wang ◽

Qinge Ma ◽

Rongrui Wei ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Schiff’S Base ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of carbamate derivatives of N-salicyloyl tryptamine as multifunctional agents for the treatment of Alzheimer's disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.114044 ◽

2021 ◽

pp. 114044

Author(s):

Dan Liu ◽

Honghua Zhang ◽

Yuying Wang ◽

Wencheng Liu ◽

Gaofeng Yin ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation ◽

Derivatives Of

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Novel salicylamide derivatives as potent multifunctional agents for the treatment of Alzheimer's disease: Design, synthesis and biological evaluation

Bioorganic Chemistry ◽

10.1016/j.bioorg.2018.11.022 ◽

2019 ◽

Vol 84 ◽

pp. 137-149 ◽

Cited By ~ 6

Author(s):

Qing Song ◽

Yan Li ◽

Zhongcheng Cao ◽

Xiaoming Qiang ◽

Zhenghuai Tan ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Salicylamide Derivatives ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis, and biological evaluation of novel xanthone-alkylbenzylamine hybrids as multifunctional agents for the treatment of Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113154 ◽

2021 ◽

Vol 213 ◽

pp. 113154

Author(s):

Zhipeng Zhang ◽

Jie Guo ◽

Maojun Cheng ◽

Weixin Zhou ◽

Yang Wan ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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Design, synthesis and biological evaluation of 4′-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2016.12.013 ◽

2017 ◽

Vol 25 (3) ◽

pp. 1030-1041 ◽

Cited By ~ 23

Author(s):

Ganyuan Xiao ◽

Yan Li ◽

Xiaoming Qiang ◽

Rui Xu ◽

Yunxiaozhu Zheng ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Biological Evaluation ◽

Design Synthesis ◽

Multifunctional Agents ◽

Synthesis And Biological Evaluation

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