BDNF Val66Met polymorphism is associated with negative symptoms in early-onset schizophrenia spectrum and other psychotic disorders

Author(s):  
G. Karacetin ◽  
B. Bayoglu ◽  
T. Eseroglu Soylemez ◽  
M. Topal ◽  
E. Bulanik Koc ◽  
...  
Author(s):  
J. Corey Williams ◽  
Hanna E. Stevens

This chapter provides a summary of a landmark study in child and adolescent psychiatry that addresses the treatment of youth with psychotic disorders. Are second generation antipsychotics superior to first generation antipsychotics in the treatment of early-onset schizophrenia spectrum disorders? Starting with that question, it describes the basics of the study, including funding, study locations, who was studied, how many patients, study design, study intervention, follow-up, endpoints including treatment response and adverse events, results, and criticism and limitations. No differences in symptom change were found between groups, but each group had a specific set of adverse events that distinguished it. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.


2014 ◽  
Vol 55 (5) ◽  
pp. 1174-1181 ◽  
Author(s):  
Barbara Remberk ◽  
Anna Katarzyna Bażyńska ◽  
Anna Krempa-Kowalewska ◽  
Filip Rybakowski

Author(s):  
Robert L. Findling ◽  
Jacqueline L. Johnson ◽  
Jon McClellan ◽  
Jean A. Frazier ◽  
Benedetto Vitiello ◽  
...  

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