scholarly journals Treating alcohol dependence with an abuse and misuse deterrent formulation of sodium oxybate: Results of a randomised, double-blind, placebo-controlled study

2021 ◽  
Vol 52 ◽  
pp. 18-30
Author(s):  
Julien Guiraud ◽  
Giovanni Addolorato ◽  
Henri-Jean Aubin ◽  
Philippe Batel ◽  
Andrea de Bejczy ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Sodium Oxybate ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals Efficacy of acamprosate in the treatment of alcohol-dependent outpatients

2003 ◽  
Vol 25 (3) ◽  
pp. 156-159 ◽  
Author(s):  
Danilo Antonio Baltieri ◽  
Arthur Guerra de Andrade
Keyword(s):  
Side Effects ◽  
Alcohol Dependence ◽  
Placebo Treatment ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo ◽  
Continuous Abstinence ◽  
Icd 10 ◽  
Alcohol Dependent

OBJECTIVE: To evaluate the efficacy and security of acamprosate in the treatment of 75 men, aged 18 to 59 years, with diagnosis of alcohol dependence according to the ICD-10. METHODS: Double-blind, placebo-controlled study, 24-week long. After a one-week detoxification period, patients were randomly divided in two groups: the first group received acamprosate (six tablets of 333 mg/d for 12 weeks) and the second group received placebo (six tablets for 12 weeks). After the first 12 weeks, patients continued the follow-up for further 12 weeks without medication. RESULTS: Patients who were receiving acamprosate showed significantly higher continuous abstinence time within the 24 weeks of treatment compared with patients who were assigned to placebo treatment (p=.017). Twenty-five percent of patients who were receiving acamprosate and 20% of the placebo-treated patients dropped out. Few side-effects were reported in both groups. CONCLUSION: Acamprosate proved to be safe and effective in treating alcohol-dependent patients and to maintain the abstinence during 24 weeks.

A Double-Blind, Placebo-Controlled Study of Olanzapine in the Treatment of Alcohol-Dependence Disorder

2004 ◽  
Vol 28 (5) ◽  
pp. 736-745 ◽  
Author(s):  
José Guardia ◽  
Lidia Segura ◽  
Begoña Gonzalvo ◽  
Lisbeth Iglesias ◽  
Carlos Roncero ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals A Double-blind, Placebo-Controlled Study of Oral Nalmefene for Alcohol Dependence

1999 ◽  
Vol 56 (8) ◽  
pp. 719 ◽  
Author(s):  
Barbara J. Mason ◽  
Fernando R. Salvato ◽  
Lauren D. Williams ◽  
Eva C. Ritvo ◽  
Robert B. Cutler
Keyword(s):  
Alcohol Dependence ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

A Randomized, Multicenter, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Aripiprazole for the Treatment of Alcohol Dependence

2008 ◽  
Vol 28 (1) ◽  
pp. 5-12 ◽  
Author(s):  
Raymond F. Anton ◽  
Henry Kranzler ◽  
Christopher Breder ◽  
Ronald N. Marcus ◽  
William H. Carson ◽  
...  
Keyword(s):  
Alcohol Dependence ◽  
Controlled Study ◽  
Efficacy And Safety ◽  
Double Blind ◽  
Double Blind Placebo

Sodium oxybate reduces pain, fatigue, and sleep disturbance and improves functionality in fibromyalgia: Results from a 14-week, randomized, double-blind, placebo-controlled study

Pain ◽  
2011 ◽  
Vol 152 (5) ◽  
pp. 1007-1017 ◽  
Author(s):  
Jon I. Russell ◽  
Andrew J. Holman ◽  
Todd J. Swick ◽  
Sarah Alvarez-Horine ◽  
Grace Y. Wang ◽  
...  
Keyword(s):  
Sleep Disturbance ◽  
Sodium Oxybate ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo

scholarly journals A double-blind, placebo-controlled study of sertraline with naltrexone for alcohol dependence

2009 ◽  
Vol 99 (1-3) ◽  
pp. 317-321 ◽  
Author(s):  
Conor K. Farren ◽  
Michael Scimeca ◽  
Ran Wu ◽  
Stephanie O. Malley
Keyword(s):  
Alcohol Dependence ◽  
Controlled Study ◽  
Double Blind ◽  
Double Blind Placebo
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