Molecular evidence for progression of nephrogenic metaplasia of the urinary bladder to clear cell adenocarcinoma

2006 ◽  
Vol 37 (1) ◽  
pp. 117-120 ◽  
Author(s):  
Arndt Hartmann ◽  
Kerstin Junker ◽  
Wolfgang Dietmaier ◽  
Sören Schröder ◽  
Diego Lopez ◽  
...  
2002 ◽  
Vol 9 (8) ◽  
pp. 467-469 ◽  
Author(s):  
Yoh Matsuoka ◽  
Tatsuya Machida ◽  
Kaoru Oka ◽  
Kazuhiro Ishizaka

Urology ◽  
2003 ◽  
Vol 62 (1) ◽  
pp. 145 ◽  
Author(s):  
Alireza Moinzadeh ◽  
Jerilyn Latini ◽  
Karim J Hamawy

2009 ◽  
Vol 133 (6) ◽  
pp. 987-991 ◽  
Author(s):  
Adebowale J. Adeniran ◽  
Pheroze Tamboli

Abstract In this short review, we discuss clear cell adenocarcinoma of the urinary bladder, a rare tumor that primarily affects women. The histogenesis of this neoplasm is uncertain; in some tumors the clinicopathologic and histologic features are suggestive of a müllerian origin. Clear cell adenocarcinoma consists of cells with abundant clear cytoplasm, arranged in solid, glandular, or tubulocystic patterns. These tumors are positive for pancytokeratin, cytokeratin 7, and CA 125 immunohistochemical stains. Patients typically present with gross hematuria, dysuria, and discharge. The natural history is poorly understood and patient outcomes remain unclear. Currently, surgery is the treatment of choice. Nephrogenic adenoma is the most important differential diagnostic consideration, followed by metastatic clear cell carcinoma.


1998 ◽  
Vol 29 (12) ◽  
pp. 1451-1456 ◽  
Author(s):  
Michael Z Gilcrease ◽  
Ruby Delgado ◽  
Frank Vuitch ◽  
Jorge Albores-Saavedra

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