Procyanidine resists the fibril formation of human islet amyloid polypeptide

2021 ◽  
Author(s):  
Jufei Xu ◽  
Ting Zheng ◽  
Xiangyi Huang ◽  
Yanan Wang ◽  
Guowei Yin ◽  
...  
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals The flanking peptides issue from the maturation of the human islet amyloid polypeptide (hIAPP) slightly modulate hIAPP-fibril formation but not hIAPP-induced cell death

Biochimie ◽  
2020 ◽  
Vol 170 ◽  
pp. 26-35 ◽  
Author(s):  
Shadai Salazar Vazquez ◽  
Bertrand Blondeau ◽  
Pierre Cattan ◽  
Mathieu Armanet ◽  
Ghislaine Guillemain ◽  
...  
Keyword(s):  
Cell Death ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Ruthenium complexes as novel inhibitors of human islet amyloid polypeptide fibril formation

Metallomics ◽  
2013 ◽  
Vol 5 (12) ◽  
pp. 1599 ◽  
Author(s):  
Lei He ◽  
Xuesong Wang ◽  
Cong Zhao ◽  
Hongfei Wang ◽  
Weihong Du
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Ruthenium Complexes ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals Time dependence of NMR observables reveals salient differences in the accumulation of early aggregated species between human islet amyloid polypeptide and amyloid-β

2018 ◽  
Vol 20 (14) ◽  
pp. 9561-9573 ◽  
Author(s):  
Anaïs R. F. Hoffmann ◽  
Lucie Caillon ◽  
Lilian Shadai Salazar Vazquez ◽  
Pierre-Alexandre Spath ◽  
Ludovic Carlier ◽  
...  
Keyword(s):  
Time Dependence ◽  
Islet Amyloid Polypeptide ◽  
Proton Nmr ◽  
Amyloid Β ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Proton NMR shows that IAPP fibril formation does not involve the accumulation of early aggregated species, in contrast with Aβ.

scholarly journals Effects of beta cell granule components on human islet amyloid polypeptide fibril formation

FEBS Letters ◽  
1996 ◽  
Vol 379 (3) ◽  
pp. 203-206 ◽  
Author(s):  
Per Westermark ◽  
Zhan-Chun Li ◽  
Gunilla T. Westermark ◽  
Arnold Leckström ◽  
Donald F. Steiner
Keyword(s):  
Beta Cell ◽  
Islet Amyloid Polypeptide ◽  
Fibril Formation ◽  
Human Islet ◽  
Cell Granule ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

scholarly journals Binuclear ruthenium complexes inhibit the fibril formation of human islet amyloid polypeptide

RSC Advances ◽  
2017 ◽  
Vol 7 (30) ◽  
pp. 18512-18522 ◽  
Author(s):  
Gehui Gong ◽  
Wenji Wang ◽  
Weihong Du
Keyword(s):  
Islet Amyloid Polypeptide ◽  
Ruthenium Complexes ◽  
Fibril Formation ◽  
Human Islet ◽  
Islet Amyloid ◽  
Human Islet Amyloid Polypeptide

Binuclear ruthenium complexes reverse the aggregation of human islet amyloid polypeptide.

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