The significance of inclusion morphology and composition in governing hydrogen transportation and trapping in steels

2021 ◽  
Author(s):  
Zhixian Peng ◽  
Jing Liu ◽  
Feng Huang ◽  
Shiqi Zhang ◽  
Qian Hu ◽  
...  
Keyword(s):  
Inclusion Morphology

Effect of inclusion morphology on the densification of TA6V powder reinforced with TiB2 inclusions

1994 ◽  
pp. 197-203
Author(s):  
P. Thibault ◽  
D. Bouvard ◽  
P. Stutz ◽  
R. Baccino
Keyword(s):  
Inclusion Morphology

CHeAr variations within a dunite nodule as a function of fluid inclusion morphology

1994 ◽  
Vol 128 (3-4) ◽  
pp. 243-258 ◽  
Author(s):  
P.G. Burnard ◽  
F. Stuart ◽  
G. Turner
Keyword(s):  
Fluid Inclusion ◽  
Inclusion Morphology

Effect of inclusion morphology on the densification of powder composites

1998 ◽  
Vol 46 (11) ◽  
pp. 3905-3913 ◽  
Author(s):  
F. Delie ◽  
D. Bouvard
Keyword(s):  
Powder Composites ◽  
Inclusion Morphology

scholarly journals Effects of Inclusion Morphology on Growth of Built-up Edge in Low Carbon Free Cutting Steels

2010 ◽  
Vol 76 (10) ◽  
pp. 1166-1170
Author(s):  
Naoki MATSUI ◽  
Tatsuya HASEGAWA ◽  
Junsuke FUJIWARA
Keyword(s):  
Low Carbon ◽  
Inclusion Morphology

scholarly journals Genetic Polymorphisms and Molecular Mechanisms Mediating Oncolytic Potency of Reovirus Strains

2019 ◽  
Author(s):  
Adil Mohamed ◽  
Derek R. Clements ◽  
Prathyusha Konda ◽  
Shashi A. Gujar ◽  
Patrick W. Lee ◽  
...  
Keyword(s):  
Molecular Mechanisms ◽  
Cell Binding ◽  
Host Cell Signaling ◽  
Mammalian Orthoreovirus ◽  
Inclusion Morphology ◽  
Viral Inclusion ◽  
Commercial Sources ◽  
Reovirus Replication

ABSTRACTThe Dearing strain of Mammalian orthoreovirus (T3D) is undergoing clinical trials as an oncolytic virotherapeutic agent. In this study, a comprehensive phenotypic and genetic comparison of T3D virus stocks from various laboratories and commercial sources revealed that T3D laboratory strains differ substantially in their oncolytic activitiesin vitroandin vivo. Superior replication of the most-oncolytic T3D lab strain was attributed to several mechanistic advantages: virus-cell binding, viral RNA transcriptase activity, viral inclusion morphology, and differential activation of RIG-I versus NFκB-dependent signalling pathways. Viral S4, M1 and L3 gene segments were each independently associated with a distinct mechanistic advantage. Furthermore, the specific missense polymorphisms that governed replication potency were identified, and utilized to generate a hybrid of T3D laboratory strains with further-augmented replication in tumor cells. Together, the results depict an elaborate balance between reovirus replication and host-cell signaling to achieve optimal oncolytic reovirus efficacy.

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