Dose-volume modeling of salivary function in patients with head and neck cancer receiving radiation therapy

2004 ◽  
Vol 60 (1) ◽  
pp. S189
Author(s):  
A. Blanco ◽  
J.O. Deasy ◽  
I. El Naqa ◽  
G.E. Franklin
Keyword(s):  
Radiation Therapy ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Dose Volume ◽  
Salivary Function ◽  
Volume Modeling

Dose–volume modeling of salivary function in patients with head-and-neck cancer receiving radiotherapy

2005 ◽  
Vol 62 (4) ◽  
pp. 1055-1069 ◽  
Author(s):  
Angel I. Blanco ◽  
K.S. Clifford Chao ◽  
Issam El Naqa ◽  
Gregg E. Franklin ◽  
Konstantin Zakarian ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Dose Volume ◽  
Salivary Function ◽  
Volume Modeling

scholarly journals Does Dose Volume Histogram of Parotid Glands Correlate with Xerostomia Radiation Therapy Oncology Group Scores in Locoregionally Advanced Head and Neck Cancer Patients Treated with Intensity-Modulated Radiation Therapy?

2020 ◽  
Author(s):  
Sajal Goel ◽  
Ritu Bhutani ◽  
Vivek Bansal ◽  
Ruchika Goel
Keyword(s):  
Radiation Therapy ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Radiation Therapy Oncology Group ◽  
Intensity Modulated Radiation Therapy ◽  
Advanced Head ◽  
Dose Volume Histogram ◽  
Parotid Glands ◽  
Dose Volume

Abstract Introduction Xerostomia is an imminent complication of head and neck radiotherapy best assessed subjectively. This study aimed to evaluate the effects of sparing parotid glands with intensity-modulated radiation therapy (IMRT) on subjective xerostomia scores in patients with locoregionally advanced head and neck cancer. Subjects and Methods This is a prospective longitudinal study conducted in an outpatient department setting. A total of 43 patients with head and neck cancer were planned with IMRT as per the ICRU 62 (International Commission on Radiation Units and Measurement Report 62). The constraints to ipsilateral and contralateral parotid glands were 35 and 25 Gy, respectively. Treatment plan was assessed for doses to 100, 67, 50, and 33% volume of individual parotid glands. Patients were subjectively assessed using the Amosson’s Questionnaire and graded as per Eisbruch’s xerostomia Radiation Therapy Oncology Group scores. Dose volume histogram (DVH) was plotted and correlated with grades of xerostomia postradiation at 1, 3, 6, 9 and 12 months follow-ups. Statistical analysis was performed suing SPSS version 16, chi-square test, and one-way analysis of variance test. Results No statistically significant correlation between mean dose of radiation, volume of the parotid glands, and grades of xerostomia was noted postradiation. A statistically significant improvement in grades of xerostomia between 3 and 6 months (p = 0.0), 3 and 9 months (p = 0.020), 6 and 9 months (p = 0.009), 6 and 12 months (p = 0.05), and 9 and 12 months (p = 0.00) was noted. Recovery in grades was noted at 9 months. Conclusion There is no statistically significant direct correlation between DVH of the parotid glands and grades of xerostomia, although recovery in grades was statistically significant at 9 months.

scholarly journals Acute Toxicity and Preliminary Clinical Outcomes of Concurrent Radiation Therapy and Weekly Docetaxel and Daily Cisplatin for Head and Neck Cancer

2005 ◽  
Vol 35 (11) ◽  
pp. 639-644 ◽  
Author(s):  
Yoshizumi Kitamoto ◽  
Tetsuo Akimoto ◽  
Hitoshi Ishikawa ◽  
Tetsuo Nonaka ◽  
Hiroyuki Katoh ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Head And Neck Cancer ◽  
Acute Toxicity ◽  
Head And Neck ◽  
Clinical Outcomes ◽  
Neck Cancer ◽  
Weekly Docetaxel
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