scholarly journals TCT-113: Safety and Efficacy of Balloon Atrial Septostomy for Advanced Pulmonary Hypertension in Patients Failing Prostanoid Therapy

2011 ◽  
Vol 58 (20) ◽  
pp. B33
Circulation ◽  
1995 ◽  
Vol 91 (7) ◽  
pp. 2028-2035 ◽  
Author(s):  
Diane Kerstein ◽  
Paul S. Levy ◽  
Daphne T. Hsu ◽  
Allan J. Hordof ◽  
Welton M. Gersony ◽  
...  

2019 ◽  
Vol 60 (6) ◽  
pp. 384-386 ◽  
Author(s):  
Alexandra Arvanitaki ◽  
George Giannakoulas ◽  
Sophia Anastasia Mouratoglou ◽  
Christos Feloukidis ◽  
Haralambos Karvounis ◽  
...  

2019 ◽  
Vol 34 (1) ◽  
pp. 283-288
Author(s):  
Justin Allen ◽  
Nathan Peterson ◽  
Kirstie Barrett ◽  
Anthony Llamas

2020 ◽  
Vol 10 (4) ◽  
pp. 204589402095897
Author(s):  
Paul J. Critser ◽  
Patrick D. Evers ◽  
Eimear McGovern ◽  
Michelle Cash ◽  
Russel Hirsch

Balloon atrial septostomy is a palliative procedure currently used to bridge medically refractory pulmonary hypertension patients to lung transplantation. In the current report, we present balloon atrial septostomy as an initial therapy for high-risk pediatric pulmonary hypertension patients at our institution. Nineteen patients with median age of 4.3 years (range 0.1–14.3 years) underwent balloon atrial septostomy during initial admission for pulmonary hypertension. There were no procedural complications or deaths within 24 h of balloon atrial septostomy. Patients were followed for a median of 2.6 years (interquartile range 1.0–4.8 years). Three (16%) patients died, 3 (16%) underwent lung transplantation, and 1 (5%) underwent reverse Potts shunt. Transplant-free survival at 30 days, 1 year, and 3 years was 84%, 76%, and 67% respectively. This single-center experience suggests early-BAS in addition to pharmacotherapy is safe and warrants consideration in high-risk pediatric pulmonary hypertension patients.


2001 ◽  
Vol 52 (4) ◽  
pp. 530-534 ◽  
Author(s):  
Mauro Moscucci ◽  
Ismail T. Dairywala ◽  
Stanley Chetcuti ◽  
Biju Mathew ◽  
Peng Li ◽  
...  

1997 ◽  
Vol 7 (3) ◽  
pp. 131-133
Author(s):  
Ann M Hayden

The prognosis for patients with pulmonary hypertension is extremely poor. Predictors of poor prognosis among these patients include a cardiac index less than 2.8 L/m/m2, a mean pulmonary artery pressure higher than 50 mm Hg, a mean right atrial pressure more than 10 mm Hg, and PaO2 less than 70 mm Hg. Balloon atrial septostomy was performed as a palliative procedure in six patients with pulmonary hypertension to limit further deterioration while they awaited lung transplantation. The goal of balloon atrial septostomy was to increase cardiac output while limiting the reduction in systemic oxygen saturation to less than 10% of baseline. This procedure may prove to be a valuable adjunct to reduce morbidity and mortality from right ventricular failure for pulmonary hypertension candidates awaiting lung transplantation.


2018 ◽  
Vol 28 (12) ◽  
pp. 1421-1425
Author(s):  
Fabio Savorgnan ◽  
Nicholas B. Zaban ◽  
Justin J. Elhoff ◽  
Michael M. Ross ◽  
John P. Breinholt

AbstractBackgroundBalloon atrial septostomy is performed in infants with dextro-transposition of the great arteries to improve oxygenation before surgery. It is performed in the catheterisation laboratory with fluoroscopy or at the bedside using echocardiography. It is unclear whether procedural safety and efficacy is superior in one location versus the other, although the bedside procedure may improve resource utilisation and present an opportunity for reducing cost. This study compares safety and efficacy of atrial septostomy performed at the patient’s bedside versus the catheterisation laboratory.MethodsNeonates with dextro-transposition of the great arteries who underwent balloon atrial septostomy from October, 2000 to January, 2014 were included. Medical and procedural records, echocardiograms, and catheterisation data were reviewed. Comparisons between the two procedural locations included patient demographics, pre- and post-procedure oxygen saturations, and outcomes. Complications reviewed included bleeding, arrhythmia, cardiac trauma, stroke, and death. Coronary artery evaluations were recorded. T-tests were used for continuous variables, and Fisher’s exact tests were used for all categorical variables. Wilcoxon rank sum and analysis of covariance modelling were used for time variables and oxygen saturation, respectively.ResultsA total of 88 infants met the inclusion criteria. Among them, 53 underwent septostomy at the bedside and 35 underwent septostomy in the catheterisation laboratory. No safety or outcome benefit was identified between the two procedural locations.ConclusionSeptostomy performed at the bedside and in the catheterisation laboratory had similar outcomes and efficacy. Further, bedside septostomy has the advantage of no radiation exposure, and obviating risks with patient transfer from the ICU to the catheterisation laboratory.


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