Insulin Pump Therapy for Children and Adolescents with Type 1 Diabetes Mellitus: A Description of the Changes in Quality of Life, and Metabolic Parameters and Bmi Percentile Prior to and Post Initiation of Insulin Pump Therapy

2009 ◽  
Vol 109 (9) ◽  
pp. A11
Author(s):  
R.B. Sutherland ◽  
P. Rothpletz-Puglia ◽  
R. Touger-Decker ◽  
J. Ziegler ◽  
D. Rigassio Radler ◽  
...  
2018 ◽  
Vol 20 (6) ◽  
pp. 420-426 ◽  
Author(s):  
Dmitry N. Laptev ◽  
Valentina A. Peterkova

Rationale: Healthcare access plays a significant role in the improvement and maintaining of glycemic control and quality of life in type 1 diabetes mellitus (T1DM) patients on continuous subcutaneous insulin infusion (CSII). Aims: The aim of the study was to evaluate the feasibility of remote support in children and adolescents with type 1 diabetes mellitus (T1DM) and its effect on glycemic control and quality of life. Materials and methods: In 40 children and adolescents (132,7 years, 18/22 m/f) on CSII with inadequately controlled T1DM (HbA1c7,5%) we evaluated the effectiveness of telemedical support (TS), as compared with conventional support (CS). Parameters of glycemic control (HbA1c, average glycemia, SD, etc.) and quality of a life were obtained on follow-up visits. Patients and their parents in ТМ group twice a month sent their insulin pump data using to CSII center and diabetologists sent back their advice via e-mail, phone or Skype. The primary end point was the change from the baseline HbA1c level and the proportion of patients achieving HbA1c of less than 7.5%. Results: At 24 weeks, the baseline mean HbA1c (8.7% in the two study groups) had decreased to 7.7% in the TS group, as compared with 8.4% in the CS group (P0,05). The proportion of patients who reached the HbA1c target (7,5%) was greater in the TS group (50%) than in the CS group (20%, p0,05). A number of quality of life indicators for both parents and children with T1DM at the end of the study compared to baseline significantly increased in the TS group compared with the TC group (p0.05). During the study period rate of severe hypoglycemia and DKA in TS group (0 and 10 cases per 100 person-years) did not differ significantly from that in CS group (0 and 20 cases per 100 person-years, P0,05). Conclusion: In children with inadequately controlled T1DM, telemedical support proved to be feasible and resulted in significant improvement in glucose control (HbA1c, glucose variability) and quality of life without the increase in the incidence of DKA and severe glycemia.


2014 ◽  
Vol 16 (11) ◽  
pp. 735-741 ◽  
Author(s):  
Davide Brancato ◽  
Mattia Fleres ◽  
Vito Aiello ◽  
Gabriella Saura ◽  
Alessandro Scorsone ◽  
...  

2009 ◽  
Vol 12 (3) ◽  
pp. 60-63
Author(s):  
Elena Efimovna Petryaykina ◽  
Olga Viktorovna Dukhareva ◽  
Irina Georgievna Rybkina ◽  
Ekaterina Alexandrovna Pronina ◽  
Tatiana Dmitrievna Mikhaylova ◽  
...  

Aim. To assess dynamics of glycated hemoglobin levels and insulin doses per kg bw in children and adolescents with poorly controlled type 1 diabetes mellitus using insulin pumps. Materials and methods. Retrospective analysis of HbA1c levels and insulin doses per kg bw in children aged 2-17 years with DM1 (mean duration 5.3?3.1) before and 18 months after onset of insulin pump therapy (Medtronic Minimed 712 and 722) with a short-acting insulin analog Novopramid (Novo Nordisk) or Humalog (Ely Lilly) given to 55 (52,4%) and 50 (47,6%) of the patients respectively. НbА1с level and mean daily insulin dose per kg bw were determined when a patient visited the doctors office every 3 months. Results. Insulin pump therapy in patients with initially poorly controlled DM1 resulted in a decrease of HbA1c from 9.8?0.8 to 7,8?0,5% within 18 months after its beginning (p


2009 ◽  
Vol 12 (3) ◽  
pp. 57-59 ◽  
Author(s):  
Nina Viktorovna Bolotova ◽  
Olga Viktorovna Kompaniets ◽  
Natalya Yur'evna Filina ◽  
Natalya Valer'evna Nikolaeva

Aim. To assess quality of life (QL) in children and adolescents with type 1 diabetes mellitus (DM1) depending on its duration, mode of insulin administration,and degree of social adaptation. Materials and methods. Generic Core Scale and Diabetes Module of Pediatric Quality of Life Questionnaire were used to estimate QL in 72 diabeticchildren and adolescents aged 5-18 yr with the participation of one of the parents. Patients with severe concomitant pathology were not includedin the study. Results. Overall QL score in children and adolescents with DM1 was 73,043?1,24. The psycho-social activity of most patients in all age groups was ratherhigh in contrast to suppressed physical functions due to complications of DM1 ten or more years in duration (51,4?9,19 scores). The psycho-emotionalstate was less dependent on negative effects of the disease. Patients using an insulin pump had on the whole better QL than those receiving intensiveinsulin therapy (82 and 72 points respectively, p


2021 ◽  
Vol 17 (4) ◽  
pp. 287-292
Author(s):  
A.B. Tashmanova ◽  
G.N. Rakhimova ◽  
S.F. Berkinbaev

Background. Currently, there is no specialized structured program in the world for group training of patients with type 1 diabetes mellitus receiving insulin pump therapy. The purpose of this work was to evaluate the effectiveness of a modified training program in achieving target glycemic levels in children and adolescents with type 1 diabetes mellitus on insulin pump therapy. Material and methods. The training was carried out at the “School of type 1 diabetes mellitus” at the Children’s Clinical Hospital No. 2 in Almaty on an outpatient basis for five days. During the training, a modified program was used, which included all training sections. The survey enrolled 125 children and adolescents with type 1 diabetes mellitus, 68 of them were included in the group of a modified educational program, who studied annually at the “School of type 1 diabetes mellitus”. The group without training (controls) consisted of 57 children and adolescents with type 1 diabetes mellitus, who were trained at the “School of type 1 diabetes mellitus” by the traditional method. All subjects were tested on the basis of a questionnaire, which included 30 key questions on self-control of insulin pump therapy and bread units before and after training. Results. Sixty-eight patients with a modified training program were divided into two subgroups depending on the method of assessing glycemia. The compensation was evaluated by determining the le­vel of glycated hemoglobin (HbA1c). Target therapy levels were better in the modified learning groups than in the control group, which confirms the greater role of motivated parents in the control of type 1 diabetes mellitus, with frequent blood glucose measurements on FreeStyle Libre sensors. Conclusions. The creation of a modified structured training program for patients with type 1 diabetes mellitus, taking into account individual characteristics, as well as cultu­ral and national traditions, is relevant and timely.


2019 ◽  
Vol 2 (1) ◽  
pp. 20-21
Author(s):  
Jan Broz ◽  
Denisa Janickova Zdarska ◽  
Michal Policar ◽  
Viera Donicova ◽  
Marek Brabec ◽  
...  

Diabetes ◽  
2021 ◽  
Vol 70 (Supplement 1) ◽  
pp. 701-P
Author(s):  
DAVID N. O’NEAL ◽  
NISHA VENKATESH ◽  
KATRIN BROWN ◽  
ELIF I. EKINCI ◽  
SPIROS FOURLANOS ◽  
...  

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