Leukotriene Receptor Antagonists in Allergic Eye Disease: A Systematic Review and Meta-analysis

2013 ◽  
Vol 1 (1) ◽  
pp. 65-74 ◽  
Author(s):  
Jennie Gane ◽  
Roger Buckley
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Eye Disease ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor

Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis

2004 ◽  
Vol 116 (5) ◽  
pp. 338-344 ◽  
Author(s):  
Andrew M Wilson ◽  
Paul M O'Byrne ◽  
Krishnan Parameswaran
Keyword(s):  
Systematic Review ◽  
Allergic Rhinitis ◽  
Meta Analysis ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor

Leukotriene receptor antagonists for small-airway abnormalities in asthmatics: a systematic review and meta-analysis

2013 ◽  
Vol 50 (7) ◽  
pp. 695-704 ◽  
Author(s):  
Xun Chen ◽  
Ke Wang ◽  
Min Jiang ◽  
Guang-Min Nong
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Small Airway ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor ◽  
Airway Abnormalities

Treatment and Prevention of Periprosthetic Capsular Contracture in Breast Surgery With Prosthesis Using Leukotriene Receptor Antagonists: A Meta-Analysis

2021 ◽  
Author(s):  
Andrei Pașca ◽  
Eduard-Alexandru Bonci ◽  
Codruța Chiuzan ◽  
Nicoleta Monica Jiboc ◽  
Vlad Alexandru Gâta ◽  
...  
Keyword(s):  
Subgroup Analysis ◽  
Breast Surgery ◽  
Meta Analysis ◽  
Statistical Significance ◽  
Capsular Contracture ◽  
Risk Difference ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Treatment And Prevention ◽  
Leukotriene Receptor

Abstract Background Capsular Contracture (CC) is the most common long-term complication of breast surgery with prosthesis. Leukotriene Receptor Antagonists (LRAs) have been tested as a potential treatment; however, mixed results have been observed. Objectives This study presents a meta-analysis to clarify the treatment and prophylactic capabilities of LRAs in the management of CC. Methods A systematic literature search in the most popular English databases was performed to identify relevant primary publications. We included all studies that evaluated the treatment and preventive capabilities of LRAs using the Baker scale assessment. Results Six eligible studies were included based on predefined inclusion and exclusion criteria, totalling 2276 breasts, out of which 775 did not receive LRAs and 1501 did. Final pooled results showed that LRAs could help manage CC with a Risk Difference (RD) of -0.38 with the corresponding 95% Confidence Interval (CI) between -0.69 and -0.08, showing statistical significance at a Z value of 2.48, p=0.01. Subgroup analysis based on the type of drug used showed that only montelukast yielded statistical significance (RD=-0.27, 95% CI between -0.51 and -0.03, Z=2.20, p=0.03). Zafirlukast did not seem to influence CC. Further subgroup analysis based on treatment timing showed that prophylaxis was ineffective and only treatment for ongoing CC yielded statistical significance. Conclusions The current meta-analysis proved that LRAs could be used in the management of CC. Only treatment for the ongoing CC showed statistical significance. Montelukast seemed to be more efficient with a safer profile for adverse effects, while zafirlukast yielded no statistical significance.

scholarly journals Leukotriene receptor antagonists in monotherapy or in combination with antihistamines in the treatment of chronic urticaria: a systematic review

2008 ◽  
pp. 9 ◽  
Author(s):  
Gabriele Di Lorenzo ◽  
Rizzo ◽  
Leto-Barone ◽  
Lo Bianco ◽  
Ditta ◽  
...  
Keyword(s):  
Systematic Review ◽  
Chronic Urticaria ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor

Tiotropium provides greater improvements in FEV1 than leukotriene receptor antagonists as add-on to ICS in adults with asthma: a systematic review

2019 ◽  
Author(s):  
E Beck ◽  
A Kaplan ◽  
JM Fitzgerald ◽  
GE Azzi ◽  
M Engel ◽  
...  
Keyword(s):  
Systematic Review ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor

scholarly journals Leukotriene receptor antagonists for chronic urticaria: a systematic review

2014 ◽  
Vol 10 (1) ◽  
pp. 24 ◽  
Author(s):  
Nipun de Silva ◽  
Hasitha Damayanthi ◽  
Anoja Rajapakse ◽  
Chaturaka Rodrigo ◽  
Senaka Rajapakse
Keyword(s):  
Systematic Review ◽  
Chronic Urticaria ◽  
Receptor Antagonists ◽  
Leukotriene Receptor Antagonists ◽  
Leukotriene Receptor
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