The concepts of [Formula: see text]-derivations and [Formula: see text]-central derivations have been recently presented in [G. R. Biyogmam and J. M. Casas, [Formula: see text]-central derivations, [Formula: see text]-centroids and [Formula: see text]-stem Leibniz algebras, Publ. Math. Debrecen 97(1–2) (2020) 217–239]. This paper studies the notions of [Formula: see text]-[Formula: see text]-derivation and [Formula: see text]-[Formula: see text]-central derivation on Leibniz algebras as generalizations of these concepts. It is shown that under some conditions, [Formula: see text]-[Formula: see text]-central derivations of a non-Lie-Leibniz algebra [Formula: see text] coincide with [Formula: see text]-[Formula: see text]-[Formula: see text]-derivations, that is, [Formula: see text]-[Formula: see text]-derivations in which the image is contained in the [Formula: see text]th term of the lower [Formula: see text]-central series of [Formula: see text] and vanishes on the upper [Formula: see text]-central series of [Formula: see text] We prove some properties of these [Formula: see text]-[Formula: see text]-[Formula: see text]-derivations. In particular, it is shown that the Lie algebra structure of the set of [Formula: see text]-[Formula: see text]-[Formula: see text]-derivations is preserved under [Formula: see text]-[Formula: see text]-isoclinism.