[123 I]N -ω-fluoropropyl-2β-carbomethoxy-3β-(4-iodophenyl)nortropane single-photon emission computed tomography brain imaging in the diagnosis of dementia with Lewy bodies

2011 ◽  
Vol 8 (1) ◽  
pp. 74-83 ◽  
Author(s):  
Zuzana Walker ◽  
Jeffrey L. Cummings
Keyword(s):  
Computed Tomography ◽  
Dementia With Lewy Bodies ◽  
Single Photon ◽  
Photon Emission ◽  
Lewy Bodies ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Diagnosis Of Dementia ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

Efficacy of Single Photon Emission Computed Tomography in Differentiating Dementia with Lewy Bodies - A Review of Neurotransmitter and Perfusion Imaging

2009 ◽  
Vol 4 (1) ◽  
pp. 82 ◽  
Author(s):  
Shirlony Morgan ◽  
Zuzana Walker ◽  
◽  
Keyword(s):  
Computed Tomography ◽  
Dementia With Lewy Bodies ◽  
Single Photon ◽  
Photon Emission ◽  
Lewy Bodies ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Emission Computed ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

The accuracy of the clinical diagnosis of dementia with Lewy bodies continues to be relatively poor. Several neuroimaging techniques have been used to facilitate a more accurate diagnosis. Thus far, functional neuroimaging has provided the most help. This article concentrates on the use of single photon emission computed tomography (SPECT) and reports on the efficacy data available from studies investigating cerebral perfusion, cardiac scintigraphy and dopaminergic neurotransmission. The results from perfusion studies are inconsistent. Cardiac scintigraphy shows more promise, but it is not yet known whether co-morbid cardiac conditions, which are common in the elderly, will limit the clinical use of this method. The radioligand123I–FP-CIT binds to dopamine transporters in nigrostriatal nerve terminals and provides a way of assessing the neurodegeneration caused by Lewy body pathology. Abnormal123I–FP-CIT has been shown to have high sensitivity and specificity in an autopsy study and a large multicentre trial. This article aims to give an overview of the topic.

Single-photon emission computed tomography in the differential diagnosis of dementia with Lewy Bodies

2015 ◽  
Vol 24 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Bogna Brockhuis ◽  
Emilia J. Sitek ◽  
Piotr Lass ◽  
Dariusz Wieczorek ◽  
Mirosława Derejko ◽  
...  
Keyword(s):  
Dementia With Lewy Bodies ◽  
Single Photon ◽  
Photon Emission ◽  
Lewy Bodies ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Diagnosis Of Dementia ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography ◽  
Differential Diagnosis Of Dementia

Contribution of Single Photon Emission Computed Tomography to the Differential Diagnosis of Dementia in a Memory Clinic

2012 ◽  
Vol 30 (4) ◽  
pp. 833-845 ◽  
Author(s):  
Adeline Rollin-Sillaire ◽  
Stéphanie Bombois ◽  
Vincent Deramecourt ◽  
Aline Steinert-Emptaz ◽  
Julia Salleron ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Memory Clinic ◽  
Single Photon Emission ◽  
Diagnosis Of Dementia ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography ◽  
Differential Diagnosis Of Dementia
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