Diagnostic Accuracy of Fine-needle Aspiration Cytology Performed in a One-stop Clinic for the Diagnosis of Breast Lesions

2018 ◽  
Vol 7 (5) ◽  
pp. S84
Author(s):  
Philippe Vielh ◽  
Isabelle Borget ◽  
Voichita Suciu
Author(s):  
Tanwi Singh ◽  
Kalpana Chandra

Increasing awareness, associated anxiety & stress among women who perceive every lump in breast as carcinoma, compels the patient to seek the medical advice. It is sometimes difficult to determine whether a suspicious lump is benign or malignant simply from clinical assessment and fine needle aspiration cytology (FNAC) is helpful in reaching definitive diagnosis. Accuracy in the diagnosis can be increased by multiple sampling of appropriate sites by ultrasonography guidance and/or mammographic localization. Breast cancer is the most common cancer in women all over India. Due to lack of awareness and almost non-existent breast screening practices, patients present with palpable breast cancers. Hence based on above findings the present study was planned for Assessment of Diagnostic Accuracy of Fine Needle Aspiration Cytology in Benign and Malignant Breast Lesions. The present study was planned in Department of Pathology, Indira Gandhi Institute of Medical Science, Patna, Bihar, India. The present study was planned from duration of march 2019 to August 2019. In the present study 50 females with breast lesion were included and evaluated in the present study. The FNAC was performed in each patient by the technique of Martin and Ellis using 21-22G needle attached to 20 ml disposable syringe and smear prepared both wet fixed in 95% ethanol and air dried. All cytology smears were stained by May Grunwald Giemsa, Papanicolaou, and hematoxylin and eosin stain. It is highly useful in screening large population as it is simple, rapid, cost effective and reliable. FNAC has few limitations and biopsy is must in cases with suspicious and atypical lumps. FNAC serves as a compliment and not a substitute to the histopathology in such cases. So, it is concluded that FNAC should be used as a routine diagnostic procedure to maximize the availability of effective health care to patients with breast lesions. Keywords: Diagnostic Accuracy, Fine Needle Aspiration, Cytology, Benign, Malignant Breast Lesions, etc.


1970 ◽  
Vol 1 (2) ◽  
pp. 108-113 ◽  
Author(s):  
S Vaidya ◽  
A Sinha ◽  
S Narayan ◽  
S Adhikari ◽  
KC Sabira

Background: A wide variety of benign and malignant tumours originate in the salivary glands and insufficient tumour cells make their diagnosis difficult in some patients. The aim of this study was to evaluate the efficacy of fine-needle aspiration cytology in the diagnosis of salivary gland lesions and to correlate cytological findings with histopathology. Materials and Methods: This was a prospective study done from September 2002 to May 2004. Fine needle aspiration cytology was performed in 58 patients with clinically significant salivary gland masses. Results: Fine needle aspiration cytology categorized 67.24% of the salivary gland lesions as neoplastic and 32.76% as non-neoplastic lesions. Amongst the neoplastic lesions, 76.9% were benign and 23.1% were malignant cases. Histopathological examination revealed that 81.05% of the cases were benign and 18.95% were malignant. Fine needle aspiration cytology had a sensitivity, specificity and diagnostic accuracy of 81.82%, 100% and 96.55%, respectively. The positive predictive value and negative predictive value was 100% and 95.9%, respectively. Conclusion: Fine needle aspiration of the salivary gland is a safe and reliable technique in the primary diagnosis of salivary gland lesions. Although, limitations are encountered while predicting specific lesions on cytology, especially when dealing with cystic and some malignant lesions, this study has shown that fine needle aspiration cytology has a high sensitivity, specificity and diagnostic accuracy in diagnosing salivary gland lesions. Keywords: Salivary glands; Fine needle aspiration cytology; Histopathology DOI: http://dx.doi.org/10.3126/jpn.v1i2.5403 JPN 2011; 1(2): 108-113


2018 ◽  
Vol 8 (3-4) ◽  
pp. 27-31
Author(s):  
Kazi Farzana Khanam ◽  
Nasima Akter ◽  
Tarana Tabashum ◽  
Abu Khalid Muhammad Maruf Raza ◽  
Asma Ul Hosna ◽  
...  

2021 ◽  
Author(s):  
Olga Guiban ◽  
Antonello Rubini ◽  
Daniele Fresilli ◽  
Giuseppe Tiziano Lucarelli ◽  
Massimo Ralli ◽  
...  

Aims: To evaluate the pre-surgical diagnostic value of Multiparametric Ultrasound (MPUS) and Fine Needle Aspiration Cytology (FNAC) in differentiating parotid gland tumors, comparing the results with histology. Materials and methods:The study enrolled 84 patients with parotid gland lesions surgically treated in a single tertiary center and evaluated by MPUS. Each patient underwent FNAC. Histological examination was considered the gold standard. Results: Histology identified 62 benign tumors and 22 malignancies. In the differential diagnosis between malignant and benign lesions, B-mode Ultrasound (US), Color-Doppler US, Contrast-Enhanced US (CEUS), Elastography (USE) and FNAC showed the following values of sensitivity: 82%, 81%, 86%, 77%, 73% respectively; specificity: 97%, 61%, 95%, 71%, 97% respectively; PPV: 90%, 43%, 86%, 50%, 89% respectively; NPV: 93%, 90%, 95%, 88%, 91% respectively; and accuracy: 89%, 71%, 90%, 78%, 84% re-spectively. Conclusions: CEUS proved to be a valid and accurate method for identifying malignant tumors of parotid gland; the combination of B-mode US with CEUS showed similar diagnostic accuracy, but better sensitivity than CEUS taken alone. USE did not improve the diagnostic performance of the B-mode US, alone or in association with CEUS; however, it revealed the highest diagnostic accuracy in the differentiation between benign lesions. FNAC demonstrated lower values in comparison with CEUS and with USE. Therefore, according to our study, MPUS could be proposed as a valid alternative to FNAC.


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