Left ventricular myocardial performance index for assessment of acute periprocedural outcomes in coronary artery disease patients after successful percutaneous coronary intervention

2014 ◽  
Vol 4 (3) ◽  
pp. 144-151
Author(s):  
C. Siva Sankara ◽  
D. Rajasekhar ◽  
K. Latheef ◽  
G. Subramanyam ◽  
V. Vanajakshamma ◽  
...  
2015 ◽  
Vol 8 (1) ◽  
pp. 270 ◽  
Author(s):  
Nahid Salehi ◽  
Mohammadreza Saidi ◽  
Alireza Rai ◽  
Farid Najafi ◽  
Seedmokhtar Javeedannejad ◽  
...  

<p><strong>BACKGROUND:<em> </em></strong>There is considerable disagreement over the effects of percutaneous coronary intervention (PCI) on left ventricular diastolic function that has necessitated the investigation of diastolic indices. The present study was conducted to evaluate left ventricular diastolic function and its indices, three months after performing the PCI procedure in patients with coronary artery disease (CAD).</p> <p><strong>METHODS:<em> </em></strong>In a quasi-experimental clinical trial study (before and after), 51 patients with CAD scheduled for elective PCI were investigated provided that their Ejection Fraction (EF) was &gt; 30%. Before and three months after PCI, echocardiography was carried out to evaluate left ventricular diastolic indices including the E/Ea as the most important criteria for diagnosis of diastolic heart failure (DHF).<strong></strong></p> <p><strong>RESULTS:<em> </em></strong>Based on the E/Ea indices and after PCI, the number of patients with DHF decreased significantly: 40 patients (78.4%) before PCI versus 28 patients (54.9%) after PCI (p&lt;0.05). The Mean and Standard error of deceleration time (DT), isovolumic relaxation time (IVRT), early diastolic mitral annulus velocity; Ea (E'), E/Ea and left ventricular ejection function (LVEF) indices underwent significant changes. In addition, MVA dur/PVA dur, PVs/PVd, and E/Ea indices had changed significantly after PCI in both genders. However, no significant difference was reported for the other indices.</p> <p><strong>CONCLUSION:<em> </em></strong>The E/Ea ratio as an important criterion for diagnosis of DHF was improved after PCI. Improvement of several other diastolic indices was observed after the PCI procedure. It can be concluded that PCI can be an effective treatment modality in patients with left ventricular diastolic indices.</p>


2021 ◽  
Vol 33 (1) ◽  
Author(s):  
Hossam Eldin M. Mahmoud ◽  
Mohamed Alsenbesy ◽  
Gehad Osama Fawzy Sayed ◽  
Abdulla Eliaw Mohamed Ali ◽  
Ahlam M. Sabra

Abstract Background Prediabetes is considered a major risk factor for diabetes mellitus (DM), leading to microvascular and cardiovascular disorders. Myocardial performance index (MPI) is a non-invasive Doppler method for the determination of global ventricular activity. We have not enough knowledge about the effect of prediabetes on the left ventricular (LV) function. We aimed to assess the MPI in prediabetic patients without coronary artery disease (CAD) utilizing echocardiography tissue Doppler imaging (TDI). Results We conducted a randomized controlled study that included fifty prediabetic patients and fifty healthy participants as the control group. All the participants were subjected to laboratory tests and echocardiography TDI to evaluate the LV systolic and diastolic functions We found that the isovolumic relaxation time (IVRT) and MPI values were significantly increased in the prediabetic patients compared to the control group (P < 0.001). In contrast, left ventricular ejection time (ET) was significantly longer in the control group than in prediabetic patients. Conclusion Prediabetes may adversely affect the LV function as assessed by MPI. Screening for prediabetes and early intervention is required for the prevention of cardiovascular morbidity and mortality.


2012 ◽  
Vol 4 (2) ◽  
pp. 127-131
Author(s):  
AK Mandal ◽  
AHK Chowdhury ◽  
AK Choudhury ◽  
AKM Monwarul Islam ◽  
B Guha

Background: Although percutaneous coronary intervention (PCI) is an excellent therapy for coronary artery disease, there is a paucity of information on the efficacy of PCI in improving diastolic function, especially in Bangladesh. Because of the high prevalence of left ventricular diastolic dysfunction in coronary artery disease patients and its probable progression to heart failure, an evaluation of the role of PCI in improving diastolic function is required. Objective of the study was to evaluate the impact of percutaneous coronary intervention on left ventricular diastolic dysfunction by Doppler echocardiography in patients with coronary artery disease. Methods: One hundred patients scheduled for elective PCI were enrolled in this study whose left ventricular systolic ejection fraction was normal or only mildly abnormal. Before PCI and 48 hours after PCI, echocardiography was done to evaluate the indices of LV diastolic function in these patients. Results: The mean age of the patients was 52 ± 8.6 years, and 90 patients were male. All had mild to moderate degree of left ventricular diastolic dysfunction. Mitral E wave velocity (58.8 cm/s ± 11.8 before treatment versus 78.1 cm/s ± 13.9, 48 hours after treatment), the peak velocity of late filling due to atrial contraction (mitral A wave velocity) (76.6 cm/s± 13.5 before treatment vs. 67.7cm/s ± 15.2 , 48 hours after treatment) , E/A ratio (0.81± 0.25 before treatment vs. 1.2 ± 0.31 , 48 hours after treatment) showed improvement after PCI. After PCI deceleration time (DT) decreased (245.6msec ±41.6 before treatment versus 175.5msec ± 31.9, 48 hours after treatment), and the difference was statistically significant (p<0.001). It is notable that early diastolic mitral annular velocity (E2 ) improved significantly 48 hours after PCI (5.9cm/s ± 1.7 before treatment vs 7.9 cm/s ±1.6, 48 hours after treatment, p < 0.001). E/ E2 ratio showed significant change 48 hours after PCI; it was statistically significant (10.5±2.8 before treatment vs 9.9 ± 2.4, 48 hours after treatment p<0.001). Conclusion: Improvement in some indices of left ventricular diastolic function after PCI indicates that PCI can be an effective treatment modality for impaired diastolic function in patients with symptomatic coronary artery disease. DOI: http://dx.doi.org/10.3329/cardio.v4i2.10456 Cardiovasc. j. 2012; 4(2): 127-131


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