scholarly journals Atom accurate structure determination of alprazolam/cyclodextrin inclusion complexes by ROESY and computational approaches

2022 ◽  
Vol 99 (1) ◽  
pp. 100299
Author(s):  
Shah Imtiaz ◽  
Syed Mashhood Ali
Keyword(s):  
Inclusion Complexes ◽  
Structure Determination ◽  
Computational Approaches ◽  
Cyclodextrin Inclusion Complexes ◽  
Cyclodextrin Inclusion

Cyclodextrin Inclusion Complexes of Two Non-Steroidal Antiinflammatory Drugs and of an Analgesic Drug

1991 ◽  
Vol 44 (6) ◽  
pp. 855 ◽  
Author(s):  
SE Brown ◽  
JH Coates ◽  
CJ Easton ◽  
SF Lincoln ◽  
Y Luo ◽  
...  
Keyword(s):  
Inclusion Complexes ◽  
Stability Constants ◽  
Analgesic Drug ◽  
Antiinflammatory Drugs ◽  
Cyclodextrin Inclusion Complexes ◽  
Spectral Changes ◽  
Cyclodextrin Inclusion ◽  
Non Steroidal Antiinflammatory Drugs ◽  
The Stability

U.v .-visible spectrophotometric studies of the interactions of Naproxen, Ibuprofen and Panadol with α-cyclodextrin , β-cyclodextrin, γ-cyclodextrin and dimethyl β- cyclodextrin enable the determination of stability constants of inclusion complexes when their formation gives rise to appreciable spectral changes. The magnitudes of the stability constants are discussed in terms of the relative sizes and the chemical natures of the cyclodextrins and the included molecules.

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