scholarly journals Model checking for additive hazards model with multivariate survival data

2007 ◽  
Vol 98 (5) ◽  
pp. 1018-1032 ◽  
Author(s):  
Guosheng Yin
Keyword(s):  
Model Checking ◽  
Survival Data ◽  
Additive Hazards Model ◽  
Additive Hazards ◽  
Multivariate Survival ◽  
Multivariate Survival Data ◽  
Hazards Model

scholarly journals High-Dimensional Mediation Analysis Based on Additive Hazards Model for Survival Data

2021 ◽  
Vol 12 ◽  
Author(s):  
Yidan Cui ◽  
Chengwen Luo ◽  
Linghao Luo ◽  
Zhangsheng Yu
Keyword(s):  
Indirect Effect ◽  
Mediation Analysis ◽  
Survival Data ◽  
Cox Model ◽  
The Cancer Genome Atlas ◽  
High Dimensional ◽  
Additive Hazards Model ◽  
Additive Hazards ◽  
Hazards Model ◽  
Positive Rate

Mediation analysis has been extensively used to identify potential pathways between exposure and outcome. However, the analytical methods of high-dimensional mediation analysis for survival data are still yet to be promoted, especially for non-Cox model approaches. We propose a procedure including “two-step” variable selection and indirect effect estimation for the additive hazards model with high-dimensional mediators. We first apply sure independence screening and smoothly clipped absolute deviation regularization to select mediators. Then we use the Sobel test and the BH method for indirect effect hypothesis testing. Simulation results demonstrate its good performance with a higher true-positive rate and accuracy, as well as a lower false-positive rate. We apply the proposed procedure to analyze DNA methylation markers mediating smoking and survival time of lung cancer patients in a TCGA (The Cancer Genome Atlas) cohort study. The real data application identifies four mediate CpGs, three of which are newly found.

Estimation of direct effects for survival data by using the Aalen additive hazards model

2011 ◽  
Vol 73 (5) ◽  
pp. 773-788 ◽  
Author(s):  
Torben Martinussen ◽  
Stijn Vansteelandt ◽  
Mette Gerster ◽  
Jacob von Bornemann Hjelmborg
Keyword(s):  
Survival Data ◽  
Additive Hazards Model ◽  
Direct Effects ◽  
Additive Hazards ◽  
Hazards Model

scholarly journals Sampling‐based estimation for massive survival data with additive hazards model

2020 ◽  
Vol 40 (2) ◽  
pp. 441-450
Author(s):  
Lulu Zuo ◽  
Haixiang Zhang ◽  
HaiYing Wang ◽  
Lei Liu
Keyword(s):  
Survival Data ◽  
Additive Hazards Model ◽  
Additive Hazards ◽  
Hazards Model

scholarly journals Regression Analysis of Additive Hazards Model With Latent Variables

2015 ◽  
Vol 110 (511) ◽  
pp. 1148-1159 ◽  
Author(s):  
Deng Pan ◽  
Haijin He ◽  
Xinyuan Song ◽  
Liuquan Sun
Keyword(s):  
Regression Analysis ◽  
Latent Variables ◽  
Additive Hazards Model ◽  
Additive Hazards ◽  
Hazards Model

Regression analysis of informative current status data with the additive hazards model

2014 ◽  
Vol 21 (2) ◽  
pp. 241-258 ◽  
Author(s):  
Shishun Zhao ◽  
Tao Hu ◽  
Ling Ma ◽  
Peijie Wang ◽  
Jianguo Sun
Keyword(s):  
Regression Analysis ◽  
Current Status Data ◽  
Current Status ◽  
Additive Hazards Model ◽  
Additive Hazards ◽  
Hazards Model ◽  
Status Data
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