Are Magnetically Controlled Growing Rods a Good Option for Collapsing Spine Deformity in Spinal Muscular Atrophy Type-2 Associated Early Onset Scoliosis?

2018 ◽  
Vol 6 (6) ◽  
pp. 811
Author(s):  
Senol Bekmez ◽  
Alper Yataganbaba ◽  
Z. Deniz Olgun ◽  
H. Gokhan Demirkiran ◽  
Muharrem Yazici
Keyword(s):  
Spinal Muscular Atrophy ◽  
Early Onset ◽  
Muscular Atrophy ◽  
Good Option ◽  
Early Onset Scoliosis ◽  
Spine Deformity ◽  
Spinal Muscular Atrophy Type ◽  
Growing Rods ◽  
Magnetically Controlled Growing Rods

Evolving Surgical Management for Early-Onset Scoliosis in Spinal Muscular Atrophy Type 1 Given Improvements in Survival

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Joseph P. Drain ◽  
Christopher A. Iobst ◽  
Reid Chambers ◽  
Crystal Seilhamer ◽  
Allan C. Beebe ◽  
...  
Keyword(s):  
Spinal Muscular Atrophy ◽  
Surgical Management ◽  
Early Onset ◽  
Muscular Atrophy ◽  
Early Onset Scoliosis ◽  
Spinal Muscular Atrophy Type

Magnetically controlled growing rods in the treatment of early-onset scoliosis

2017 ◽  
Vol 99-B (6) ◽  
pp. 708-713 ◽  
Author(s):  
P. R. P. Rushton ◽  
I. Siddique ◽  
R. Crawford ◽  
N. Birch ◽  
M. J. Gibson ◽  
...  
Keyword(s):  
Early Onset ◽  
Early Onset Scoliosis ◽  
Growing Rods ◽  
Magnetically Controlled Growing Rods

scholarly journals Improvement in Fine Manual Dexterity in Children with Spinal Muscular Atrophy Type 2 after Nusinersen Injection: A Case Series

Children ◽  
2021 ◽  
Vol 8 (11) ◽  
pp. 1039
Author(s):  
Minsu Gu ◽  
Hyun-Ho Kong
Keyword(s):  
Spinal Muscular Atrophy ◽  
Motor Function ◽  
Daily Living ◽  
Muscular Atrophy ◽  
Case Series ◽  
Manual Dexterity ◽  
Gross Motor ◽  
Spinal Muscular Atrophy Type ◽  
Gross Motor Function

Although nusinersen has been demonstrated to improve motor function in patients with spinal muscular atrophy (SMA), no studies have investigated its effect on fine manual dexterity. The present study aimed to investigate the ability of nusinersen to improve fine manual dexterity in patients with SMA type 2. A total of five patients with SMA type 2 were included. The Hammersmith Functional Motor Scale (expanded version) (HFMSE) and Purdue Pegboard (PP) tests were used to evaluate gross motor function and fine manual dexterity, respectively, until 18 months after nusinersen administration. HFMSE scores improved by 3–10 points (+13–53%) in all patients following nusinersen administration. PP scores also improved in all patients, from 4 to 9 points (+80–225%) in the preferred hand and from 3 to 7 points (+60–500%) in the non-preferred hand. These results suggest that nusinersen treatment improved both gross motor function and fine manual dexterity in children with SMA type 2. Addition of the PP test may aid in evaluating the fine manual dexterity essential for activities of daily living in these patients.

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