scholarly journals Baseline Characteristics and Vitreoretinal Interface Features in Patients with Vitreomacular Traction and Macular Hole from the MIVI-TRUST Clinical Program

2013 ◽  
Vol 16 (7) ◽  
pp. A502
Author(s):  
B. Lescrauwaet ◽  
Z. Koshy ◽  
A. Labourette ◽  
L. Duchateau
2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Irena Tsui ◽  
Carolyn K. Pan ◽  
Ehsan Rahimy ◽  
Steven D. Schwartz

Fibronectin and laminin are clinically relevant plasmin receptors in the eye. Located at the vitreoretinal interface, they are cleaved by ocriplasmin (Microplasmin, ThromboGenics, Iselin, NJ), a novel ophthalmic medication. A series of clinical trials to study ocriplasmin for the treatment of vitreoretinal diseases such as vitreomacular traction, macular hole, and exudative age-related macular degeneration are underway. The results are promising and may impact patient care.


Eye ◽  
2014 ◽  
Vol 28 (9) ◽  
pp. 1150-1150
Author(s):  
W Amoaku ◽  
P Cackett ◽  
A Tyagi ◽  
U Mahmood ◽  
J Nosek ◽  
...  

2020 ◽  
pp. 247412642096534
Author(s):  
Nathalie Massamba ◽  
Eric K. Chin ◽  
David R.P. Almeida

Purpose: We report a case of recurrent macular hole (MH) formation and spontaneous closure in the absence of any vitreoretinal interface abnormality. Methods: A 49-year-old man presented for his annual ocular examination with no specific ocular complaints. He had a history of retinal detachment in the left eye, which was treated years prior with vitrectomy and scleral buckle. During a routine follow-up, the patient was discovered to have a full-thickness MH. Optical coherence tomography revealed the formation of an MH with spontaneous closure after 3 months without intervention. One month later, the MH recurred but once again closed spontaneously over 4 months. Results: The patient remained asymptomatic during the entire follow-up without any symptoms, vision changes, or therapeutic intervention. Conclusions: To our knowledge, this is the first known case report of recurrent spontaneous opening and closure of an MH in the absence of any vitreoretinal interface abnormality, as revealed by macular optical coherence tomography imaging.


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