Abstract No. 295: Hypoxia induces a phenotypic switch of fibroblasts to myofibroblasts through a MMP-2/TIMP mediated pathway: Implications for venous stenosis formation in hemodialysis vascular access failure

2010 ◽  
Vol 21 (2) ◽  
pp. S111-S112
Author(s):  
S. Misra ◽  
A.A. Fu ◽  
K.D. Misra ◽  
U. Shergill
Keyword(s):  
Vascular Access ◽  
Phenotypic Switch ◽  
Venous Stenosis ◽  
Hemodialysis Vascular Access

scholarly journals Advanced Stent Graft Treatment of Venous Stenosis Affecting Hemodialysis Vascular Access: Case Illustrations

2016 ◽  
Vol 33 (01) ◽  
pp. 039-045 ◽  
Author(s):  
Darshan Patel ◽  
R. Lokken ◽  
James Bui ◽  
Andrew Lipnik ◽  
Ron Gaba ◽  
...  
Keyword(s):  
Stent Graft ◽  
Vascular Access ◽  
Venous Stenosis ◽  
Hemodialysis Vascular Access

scholarly journals Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model

2013 ◽  
Vol 84 (2) ◽  
pp. 338-352 ◽  
Author(s):  
Rajiv Janardhanan ◽  
Binxia Yang ◽  
Pawan Vohra ◽  
Bhaskar Roy ◽  
Sarah Withers ◽  
...  
Keyword(s):  
Vascular Access ◽  
Venous Stenosis ◽  
Hemodialysis Vascular Access ◽  
Access Model

scholarly journals Rationale and Trial Design of MesEnchymal Stem Cell Trial in Preventing Venous Stenosis of Hemodialysis Vascular Access Arteriovenous Fistula (MEST AVF Trial)

Kidney360 ◽  
2021 ◽  
pp. 10.34067/KID.0005182021
Author(s):  
Ameet K. Piryani ◽  
Sreenivasulu Kilari ◽  
Edwin Takahashi ◽  
Randall R. DeMartino ◽  
Jay Mandrekar ◽  
...  
Keyword(s):  
Upper Extremity ◽  
Vascular Access ◽  
Trial Design ◽  
Phase 1 ◽  
Neointimal Hyperplasia ◽  
Ongoing Trial ◽  
Arteriovenous Fistulas ◽  
Venous Stenosis ◽  
Hemodialysis Vascular Access ◽  
Fistula Maturation

Background: Hemodialysis arteriovenous fistulas (AVFs) are the preferred vascular access for patients on hemodialysis. In the Hemodialysis Fistula Maturation Study, 43.7% of the patients achieved unassisted maturation of their fistula without needing an intervention. Venous neointimal hyperplasia (VNH) and subsequent venous stenosis (VS) is responsible for lack of maturation. There are no therapies that can prevent VNH/VS formation. The goal of this paper is to present the background, rationale, and trial design of an innovative phase 1 / 2 clinical study that is investigating the safety of autologous adipose derived mesenchymal stem cells (AMSCs) delivered locally to the adventitia of newly created upper extremity radiocephalic (RCF) or brachiocephalic fistula (BCF). Methods: The rationale and pre-clinical studies used to obtain a physician sponsored investigational new drug trial (IND) are discussed. The trial design and endpoints are discussed. Results: This is ongoing trial which will complete this year. Conclusion: This is a phase 1 / 2 single center, randomized trial which will investigate safety and efficacy of autologous AMSCs in promoting maturation in new upper extremity AVFs.

Diagnostic ultrasound imaging of hemodialysis vascular access-related complications

Choonpa Igaku ◽  
2019 ◽  
Vol 46 (2) ◽  
pp. 171-180
Author(s):  
Hiroki KOBAYASHI ◽  
Kotaro SUEMITSU ◽  
Masayoshi NANAMI
Keyword(s):  
Ultrasound Imaging ◽  
Vascular Access ◽  
Diagnostic Ultrasound ◽  
Hemodialysis Vascular Access

Differences in Initial Hemodialysis Vascular Access Use Among Glomerulonephritis Subtypes in the United States

2016 ◽  
Vol 67 (4) ◽  
pp. 638-647 ◽  
Author(s):  
Michelle M. O’Shaughnessy ◽  
Maria E. Montez-Rath ◽  
Yuanchao Zheng ◽  
Richard A. Lafayette ◽  
Wolfgang C. Winkelmayer
Keyword(s):  
United States ◽  
Vascular Access ◽  
The United States ◽  
Hemodialysis Vascular Access

Care pathway reduces hospitalizations and cost for hemodialysis vascular access surgery

1997 ◽  
Vol 30 (4) ◽  
pp. 525-531 ◽  
Author(s):  
Bryan N. Becker ◽  
Randee Breiterman-White ◽  
William Nylander ◽  
David Van Buren ◽  
Chris Fotiadis ◽  
...  
Keyword(s):  
Vascular Access ◽  
Care Pathway ◽  
Vascular Access Surgery ◽  
Hemodialysis Vascular Access ◽  
Access Surgery

scholarly journals Medicare Reimbursement Policies and Hemodialysis Vascular Access Outcomes: A Need for Change: Table 1.

2011 ◽  
Vol 22 (3) ◽  
pp. 426-430 ◽  
Author(s):  
Michael Allon ◽  
Lesley Dinwiddie ◽  
Eduardo Lacson ◽  
Derrick L. Latos ◽  
Charmaine E. Lok ◽  
...  
Keyword(s):  
Vascular Access ◽  
Medicare Reimbursement ◽  
Hemodialysis Vascular Access
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