Rapid clearance of circulating tumor DNA during treatment with AZD9291 of a lung cancer patient presenting the resistance EGFR T790M mutation

Lung Cancer ◽  
2016 ◽  
Vol 91 ◽  
pp. 73-74 ◽  
Author(s):  
Audrey Vallée ◽  
Clarisse Audigier-Valette ◽  
Guillaume Herbreteau ◽  
Julien Merrien ◽  
Laurent Tessonnier ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patient ◽  
Lung Cancer Patient ◽  
Circulating Tumor Dna ◽  
T790m Mutation ◽  
Rapid Clearance ◽  
Tumor Dna ◽  
Egfr T790m

scholarly journals Case Report of Non-small Cell Lung Cancer Patient with EGFR T790M Mutation Treated with Th ird Generation Inhibitor

2019 ◽  
Vol 71 ◽  
pp. 49-51
Author(s):  
Dinesh Chandra Doval ◽  
Rupal Tripathi ◽  
Kumardeep Dutta Choudhury ◽  
Ajay Sharma ◽  
Ullas Batra ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patient ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Lung Cancer Patient ◽  
Growth Factor Receptor ◽  
Small Cell ◽  
Small Cell Lung ◽  
T790m Mutation ◽  
Egfr T790m

Lung cancer treatment based on the molecular classifi cation of the tumor has paved the way for multiple lines of targeted treatment, even though the development of resistance remains a major cause of concern. Epidermal growth factor receptor (EGFR) remains the poster boy for the use of targeted therapy, and the presence/absence of mutations in this gene has led to the development of inhibitors targeting specifi c mutations. We present the case of an advanced non-small cell lung cancer patient with EGFR T790M mutation treated with Osimertinib, a third-generation inhibitor.

scholarly journals Rapid decrease of circulating tumor DNA predicted the treatment effect of nivolumab in a lung cancer patient within only 5 days

2017 ◽  
Vol 22 ◽  
pp. 31-33 ◽  
Author(s):  
Yuki Iijima ◽  
Yosuke Hirotsu ◽  
Kenji Amemiya ◽  
Seishi Higashi ◽  
Yoshihiro Miyashita ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patient ◽  
Treatment Effect ◽  
Lung Cancer Patient ◽  
Circulating Tumor Dna ◽  
Rapid Decrease ◽  
Tumor Dna

scholarly journals Diagnostic accuracy of droplet digital PCR for detection of EGFR T790M mutation in circulating tumor DNA

2018 ◽  
Vol Volume 10 ◽  
pp. 1209-1218 ◽  
Author(s):  
Rui Zhang ◽  
Bojiang Chen ◽  
Xiang Tong ◽  
Ye Wang ◽  
Chengdi Wang ◽  
...  
Keyword(s):  
Diagnostic Accuracy ◽  
Digital Pcr ◽  
Circulating Tumor Dna ◽  
Droplet Digital Pcr ◽  
T790m Mutation ◽  
Tumor Dna ◽  
Egfr T790m
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