Structure-based design, synthesis and antiproliferative action of new quizoline-4-one/chalcone hybrids as EGFR inhibitors

Design, synthesis and molecular docking of α,β-unsaturated cyclohexanone analogous of curcumin as potent EGFR inhibitors with antiproliferative activity

10.1016/j.bmc.2012.11.031 ◽

2013 ◽

Vol 21 (2) ◽

pp. 388-394 ◽

Cited By ~ 23

Author(s):

Yun-Yun Xu ◽

Yi Cao ◽

Hailkuo Ma ◽

Huan-Qiu Li ◽

Gui-Zhen Ao

Keyword(s):

Molecular Docking ◽

Antiproliferative Activity ◽

Egfr Inhibitors ◽

Design, synthesis, and docking studies of quinazoline analogues bearing aryl semicarbazone scaffolds as potent EGFR inhibitors

10.1016/j.bmc.2017.04.001 ◽

2017 ◽

Vol 25 (12) ◽

pp. 3148-3157 ◽

Cited By ~ 17

Author(s):

Yuanbiao Tu ◽

Caolin Wang ◽

Shan Xu ◽

Zhou Lan ◽

Wei Li ◽

...

Keyword(s):

Docking Studies ◽

Egfr Inhibitors ◽

Design, synthesis and docking studies of benzimidazole derivatives as potential EGFR inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.04.012 ◽

2019 ◽

Vol 173 ◽

pp. 240-249 ◽

Cited By ~ 12

Author(s):

İsmail Celik ◽

Gülgün Ayhan-Kılcıgil ◽

Berna Guven ◽

Zümra Kara ◽

A. Selen Gurkan-Alp ◽

...

Keyword(s):

Docking Studies ◽

Egfr Inhibitors ◽

Benzimidazole Derivatives ◽

Design, synthesis, and biological study of 4-[(2-nitroimidazole-1H-alkyloxyl)aniline]-quinazolines as EGFR inhibitors exerting cytotoxicities both under normoxia and hypoxia

Drug Design Development and Therapy ◽

10.2147/dddt.s209481 ◽

2019 ◽

Vol Volume 13 ◽

pp. 3079-3089 ◽

Cited By ~ 1

Author(s):

Weiyan Cheng ◽

Suhua Wang ◽

Zhiheng Yang ◽

Xin Tain ◽

Yongzhou Hu

Keyword(s):

Egfr Inhibitors ◽

Biological Study ◽

In silico design, synthesis and activity of potential drug-like chrysin scaffold-derived selective EGFR inhibitors as anticancer agents

Computational Biology and Chemistry ◽

10.1016/j.compbiolchem.2019.107156 ◽

2019 ◽

Vol 83 ◽

pp. 107156 ◽

Cited By ~ 2

Author(s):

Sudhan Debnath ◽

Manupati Kanakaraju ◽

Minarul Islam ◽

Ragini Yeeravalli ◽

Debanjan Sen ◽

...

Keyword(s):

Anticancer Agents ◽

In Silico ◽

Egfr Inhibitors ◽

Potential Drug ◽

Design Synthesis ◽

In Silico Design

Design, synthesis, biological evaluation, QSAR analysis and molecular modelling of new thiazol-benzimidazoles as EGFR inhibitors

10.1016/j.bmc.2020.115657 ◽

2020 ◽

Vol 28 (18) ◽

pp. 115657

Author(s):

Aladdin M. Srour ◽

Nesreen S. Ahmed ◽

Somaia S. Abd El-Karim ◽

Manal M. Anwar ◽

Salwa M. El-Hallouty

Keyword(s):

Molecular Modelling ◽

Biological Evaluation ◽

Egfr Inhibitors ◽

Design Synthesis ◽

Qsar Analysis

Toward discovery of mutant EGFR inhibitors; Design, synthesis and in vitro biological evaluation of potent 4-arylamino-6-ureido and thioureido-quinazoline derivatives

10.1016/j.bmc.2016.05.063 ◽

2016 ◽

Vol 24 (16) ◽

pp. 3501-3512 ◽

Cited By ~ 14

Author(s):

Samar Mowafy ◽

A. Galanis ◽

Zainab M. Doctor ◽

Raymond M. Paranal ◽

Deena S. Lasheen ◽

...

Keyword(s):

Biological Evaluation ◽

Egfr Inhibitors ◽

Design Synthesis ◽

Quinazoline Derivatives ◽

Mutant Egfr

Synthesis And Biological Evaluation

Design, synthesis and biological evaluation of aminopyrimidine derivatives bearing a 4,5,6,7-tetrahydrothieno [3,2-c]pyridine as potent EGFR inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113845 ◽

2021 ◽

pp. 113845

Author(s):

Yingxue Li ◽

Yaoyao Chang ◽

Jianfang Fu ◽

Rongcai Ding ◽

Lingyun Zhang ◽

...

Keyword(s):

Biological Evaluation ◽

Egfr Inhibitors ◽

Design Synthesis ◽

Design, synthesis, and docking studies of afatinib analogs bearing cinnamamide moiety as potent EGFR inhibitors

10.1016/j.bmc.2016.02.017 ◽

2016 ◽

Vol 24 (7) ◽

pp. 1495-1503 ◽

Cited By ~ 11

Author(s):

Yuanbiao Tu ◽

Yiqiang OuYang ◽

Shan Xu ◽

Yan Zhu ◽

Gen Li ◽

...

Keyword(s):

Docking Studies ◽

Egfr Inhibitors ◽

Design, Synthesis and Structure-Activity Relationships of Novel Diaryl Urea Derivatives as Potential EGFR Inhibitors

Molecules ◽

10.3390/molecules21111572 ◽

2016 ◽

Vol 21 (11) ◽

pp. 1572 ◽

Cited By ~ 8

Author(s):

Nan Jiang ◽

Yanxin Bu ◽

Yu Wang ◽

Minhua Nie ◽

Dajun Zhang ◽

...

Keyword(s):

Egfr Inhibitors ◽

Urea Derivatives ◽

Design Synthesis ◽

Structure Activity Relationships ◽

Structure Activity