Metabolic activation of 10-aza-substituted benzo[a]pyrene by cytochrome P450 1A2 in human liver microsomes

2004 ◽  
Vol 557 (2) ◽  
pp. 159-165 ◽  
Author(s):  
Katsuya Yamada ◽  
Takayoshi Suzuki ◽  
Atsushi Hakura ◽  
Takaharu Mizutani ◽  
Ken-ichi Saeki
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Metabolic Activation ◽  
Human Liver Microsomes ◽  
Cytochrome P450 1A2

Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes

2004 ◽  
Vol 68 (4) ◽  
pp. 773-782 ◽  
Author(s):  
Bertrand Piver ◽  
Maude Fer ◽  
Xavier Vitrac ◽  
Jean-Michel Merillon ◽  
Yvonne Dreano ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cytochrome P450 1A2

Activation of Heterocyclic Aromatic Amines by Rat and Human Liver Microsomes and by Purified Rat and Human Cytochrome P450 1A2†

1998 ◽  
Vol 11 (8) ◽  
pp. 925-936 ◽  
Author(s):  
Robert J. Turesky ◽  
Anne Constable ◽  
Janique Richoz ◽  
Nathalia Varga ◽  
Jovanka Markovic ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Aromatic Amines ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Heterocyclic Aromatic Amines ◽  
Cytochrome P450 1A2 ◽  
Human Cytochrome

Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes

Xenobiotica ◽  
2009 ◽  
Vol 00 (00) ◽  
pp. 090901052053001-8
Author(s):  
K. Murai ◽  
H. Yamazaki ◽  
K. Nakagawa ◽  
R. Kawai ◽  
T. Kamataki
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Cancer Drug ◽  
Anti Cancer ◽  
Cytochrome P450 2A6

Selegiline Metabolism and Cytochrome P450 Enzymes:In vitro Study in Human Liver Microsomes*

2000 ◽  
Vol 86 (5) ◽  
pp. 215-221 ◽  
Author(s):  
Paivi Taavitsainen ◽  
Markku Anttila ◽  
Leena Nyman ◽  
Hari Karnani ◽  
Jarmo S. Salonen ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Human Liver ◽  
Liver Microsomes ◽  
Human Liver Microsomes ◽  
Vitro Study
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