Purine P2Y receptors in ATP-mediated regulation of non-quantal acetylcholine release from motor nerve endings of rat diaphragm

2011 ◽  
Vol 71 (3) ◽  
pp. 219-225 ◽  
Author(s):  
Artem I. Malomouzh ◽  
Eugeny E. Nikolsky ◽  
František Vyskočil
Keyword(s):  
Acetylcholine Release ◽  
Motor Nerve ◽  
P2y Receptors ◽  
Nerve Endings ◽  
Rat Diaphragm ◽  
Quantal Acetylcholine Release

scholarly journals Ovalbumin-induced sensitization affects non-quantal acetylcholine release from motor nerve terminals and alters contractility of skeletal muscles in mice

2009 ◽  
Vol 94 (2) ◽  
pp. 264-268 ◽  
Author(s):  
Alexander Y. Teplov ◽  
Sergey N. Grishin ◽  
Marat A. Mukhamedyarov ◽  
Airat U. Ziganshin ◽  
Andrey L. Zefirov ◽  
...  
Keyword(s):  
Skeletal Muscles ◽  
Acetylcholine Release ◽  
Motor Nerve ◽  
Nerve Terminals ◽  
Motor Nerve Terminals ◽  
Quantal Acetylcholine Release

scholarly journals Non-quantal acetylcholine release at the neuromuscular junction

2009 ◽  
pp. 763-784
Author(s):  
F Vyskočil ◽  
AI Malomouzh ◽  
EE Nikolsky
Keyword(s):  
Skeletal Muscles ◽  
Acetylcholine Release ◽  
Chloride Transport ◽  
Motor Nerve ◽  
Basic Research ◽  
Motor Nerve Terminal ◽  
Receptor Desensitization ◽  
Quantal Acetylcholine Release ◽  
Endplate Potentials ◽  
Developing Muscle

There are two principal mechanisms of acetylcholine (ACh) release from the resting motor nerve terminal: quantal and nonquantal (NQR); the former being only a small fraction of the total, at least at rest. In the present article we summarize basic research about the NQR that is undoubtedly an important trophic factor during endplate development and in adult neuromuscular contacts. NQR helps to eliminate the polyneural innervation of developing muscle fibers, ensures higher excitability of the adult subsynaptic membrane by surplus polarization and protects the RMP from depolarization by regulating the NO cascade and chloride transport. It shortens the endplate potentials by promoting postsynaptic receptor desensitization when AChE is inhibited during anti-AChE poisoning. In adult synapses, it can also activate the electrogenic Na+/K+-pump, change the degree of synchronization of quanta released by the nerve stimulation and affects the contractility of skeletal muscles.

scholarly journals Ecto‐AMP Deaminase Blunts the ATP‐Derived Adenosine A 2A Receptor Facilitation of Acetylcholine Release at Rat Motor Nerve Endings

2003 ◽  
Vol 549 (2) ◽  
pp. 399-408 ◽  
Author(s):  
M. Teresa Magalhães‐Cardoso ◽  
M. Fátima Pereira ◽  
Laura Oliveira ◽  
J. A. Ribeiro ◽  
Rodrigo A. Cunha ◽  
...  
Keyword(s):  
Acetylcholine Release ◽  
Motor Nerve ◽  
Nerve Endings ◽  
Amp Deaminase
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