RENAL OSTEODYSTROPHY IN PATIENTS WITH CHRONIC RENAL FAILURE AND SECONDARY HYPERPARATHYROIDISM: A CASE SERIES

2021 ◽  
Vol 132 (1) ◽  
pp. e46
Author(s):  
A Subarnbhesaj ◽  
I Riyachan ◽  
W Sarideechaigul ◽  
P Klanrit
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Secondary Hyperparathyroidism ◽  
Renal Osteodystrophy ◽  
Case Series

Renal Osteodystrophy in Children with Chronic Renal Failure: An Unexpectedly Common and Incapacitating Complication

PEDIATRICS ◽  
1982 ◽  
Vol 70 (5) ◽  
pp. 742-750 ◽  
Author(s):  
Anthony C. Hsu ◽  
Sang Whay Kooh ◽  
Donald Fraser ◽  
William A. Cumming ◽  
Victor L. Fornasier
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Renal Osteodystrophy ◽  
Age At Onset ◽  
Growth Zone ◽  
Growth Patterns ◽  
Bone Lesions ◽  
Older Children ◽  
Before And After ◽  
End Stage

The incidence, age at onset, and progression of the biochemical, radiographic, and histologic characteristics of renal osteodystrophy were studied in 50 children in whom chronic renal failure had been recently diagnosed. During a ten-year observation period, 19 patients progressed to end-stage renal failure and radiographic signs of renal osteodystrophy developed in 15 of these (79%). Renal osteodystrophy developed in all nine patients whose chronic renal failure was diagnosed before 3 years of age and in six of the ten children with later onset of failure. The mean interval from diagnosis of renal failure to development of osteodystrophy was 1.4 years. Radiographically, growth zone lesions predominated in the younger children, whereas cortical erosions were more prevalent in the older children. Histologic examination, performed in 38 patients, showed both defective mineralization and excessive resorption and was a more sensitive diagnostic index than radiography. Noticeable deformities developed in one third of the patients with osteodystrophy, despite medical treatment including vitamin D2 therapy. Deformities were particularly frequent and Severe in patients whose renal failure developed in infancy. In all 13 patients whose growth patterns were studied before and after osteodystrophy developed, the onset of bone lesions was associated with a deterioration of growth, indicating that osteodystrophy plays a major role in causing the growth retardation commonly observed in children with chronic renal failure.

scholarly journals mRNA expression of preproPTH and growth-related genes in secondary hyperparathyroidism in chronic renal failure patients. Effect of 1,25(OH)2D3.

1995 ◽  
Vol 28 (1) ◽  
pp. 69-75
Author(s):  
Haruyuki Hayashi ◽  
Yasubumi Irie ◽  
Kazuo Yokozeki ◽  
Susumu Kobayashi ◽  
Yasushi Ito ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Secondary Hyperparathyroidism ◽  
Mrna Expression

Secondary Hyperparathyroidism

2019 ◽  
Author(s):  
Anna C Beck ◽  
Sonia L Sugg
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Secondary Hyperparathyroidism ◽  
Total Parathyroidectomy ◽  
Indications For Surgery ◽  
Subtotal Parathyroidectomy ◽  
Diagnostic Work ◽  
Work Up ◽  
Hungry Bone ◽  
Diagnostic Work Up

Secondary hyperparathyroidism is defined and its pathophysiology, delineated. Key components of the diagnostic work-up, medical management, and indications for surgery are described. The operative approach and controversy on extent of parathyroidectomy are discussed. This review contains 3 figures, 1 tables, and 24 references.  Key Words: autotransplantation, calciphylaxis, chronic renal failure, cryopreservation, hungry bone syndrome, hypocalcemia, secondary hyperparathyroidism, subtotal parathyroidectomy, total parathyroidectomy

Secondary Hyperparathyroidism

2019 ◽  
Author(s):  
Anna C Beck ◽  
Sonia L Sugg
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Secondary Hyperparathyroidism ◽  
Total Parathyroidectomy ◽  
Indications For Surgery ◽  
Subtotal Parathyroidectomy ◽  
Diagnostic Work ◽  
Work Up ◽  
Hungry Bone ◽  
Diagnostic Work Up

Secondary hyperparathyroidism is defined and its pathophysiology, delineated. Key components of the diagnostic work-up, medical management, and indications for surgery are described. The operative approach and controversy on extent of parathyroidectomy are discussed. This review contains 3 figures, 1 tables, and 24 references.  Key Words: autotransplantation, calciphylaxis, chronic renal failure, cryopreservation, hungry bone syndrome, hypocalcemia, secondary hyperparathyroidism, subtotal parathyroidectomy, total parathyroidectomy

scholarly journals Sagliker syndrome in patients with secondary hyperparathyroidism and chronic renal failure: Case report

2015 ◽  
Vol 8 ◽  
pp. 127-130 ◽  
Author(s):  
Ana Mejía Pineda ◽  
María L. Aguilera ◽  
Héctor J. Meléndez ◽  
José A. Lemus ◽  
Marco A. Peñalonzo
Keyword(s):  
Renal Failure ◽  
Case Report ◽  
Chronic Renal Failure ◽  
Secondary Hyperparathyroidism
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