Frequency of Rhegmatogenous Retinal Detachment after Intravitreal Therapy in Neovascular Age-Related Macular Degeneration

2020 ◽  
Vol 4 (10) ◽  
pp. 973-978 ◽  
Author(s):  
Danny A. Mammo ◽  
Alexander L. Ringeisen ◽  
D. Wilkin Parke
2022 ◽  
Author(s):  
P. Barrett Paulk ◽  
Dala Eloubeidi ◽  
John O. Mason III ◽  
Christine A. Curcio ◽  
Jason N. Crosson ◽  
...  

Abstract Background Patients presenting with macula-off rhegmatogenous retinal detachment (RRD) with concomitant age-related macular degeneration (AMD) and their treating physicians would benefit from knowledge regarding the visual prognosis after repair. The prognosis for such patients is not well known. The purpose of this study is to compare visual outcomes in macula-off RRD in eyes with AMD versus a group of comparison eyes without AMD. Methods This was a retrospective chart review of 1,149 patients. A total of 191 eyes met study criteria, 162 non-AMD eyes (controls) and 29 AMD eyes. The main outcome measure was postoperative visual acuity in control eyes versus AMD eyes, and this was compared using Fisher’s exact test. Results There was a statistically significant difference in postoperative visual acuity by AMD status, with those without AMD having a higher frequency of Count Fingers (CF), Hand Motion (HM), Light Perception (LP), or No Light Perception (NLP) vision (p = 0.023). More specifically 5.56% of non-AMD eyes and 3.45% of AMD eyes were 20/40 or better, 77.16% of non-AMD and 55.17% of AMD eyes were worse than 20/40 and better than 20/200, 10.49% of non-AMD eyes and 37.93% of AMD eyes were 20/200 or worse, and there were 11 eyes in the non-AMD group with CF, HM, LP, or NLP vision while there was only 1 eye in the AMD group with CF vision. Conclusions Though postoperative visual acuity was worse in the non-AMD group with a higher frequency of patients having final vision of CF, HM, LP, or NLP, this is not likely a clinically significant finding. Rather, it is a function of the difference in sample size and composition between the two groups. Importantly, this study suggests AMD patients can expect similar outcomes to non-AMD patients after RRD repair. Our study suggests that approximately 58% of patients with AMD can expect to maintain functional vision better than 20/200. We conclude that AMD patients can achieve functional vision after RRD surgery, similar to those without AMD. These findings may be helpful in guiding realistic expectations of AMD patients with RRD.


Retina ◽  
2016 ◽  
Vol 36 (3) ◽  
pp. 476-482 ◽  
Author(s):  
Franck Fajnkuchen ◽  
Salomon Y. Cohen ◽  
Nathalie Thay ◽  
Sandrine Ayrault ◽  
Corinne Delahaye-Mazza ◽  
...  

2021 ◽  
Author(s):  
Alba Parrado-Carrillo ◽  
Marc Figueras-Roca ◽  
Ricardo P. Casaroli-Marano ◽  
Vuong Nguyen ◽  
Daniel Barthelmes ◽  
...  

Abstract Purpose: To implement an intravitreal therapy audit tool for neovascular age-related macular degeneration (nAMD) outcome reporting in a tertiary referral center. Methods: Implementation of an online audit tool (Fight Retinal Blindness platform) for nAMD eyes receiving anti-vascular endothelial growth factor (anti-VEGF) intravitreal therapy over a 24-month follow-up period. Data entry was compliant with the ICHOM dataset for nAMD. These data included visual acuity (VA), eye conditions, injection drug and number of injections. Subgroup analysis was performed for treatment-naive (TN) and previously treated (PT) eyes. Results: 234 eyes (191 patients) were included in the study. No significant differences were observed in the subgroup analysis in mean baseline VA (logMAR letters: 58.8 TN vs 62.7 PT, p= 0.081) or final VA at 12 months (TN 61.4 vs PT 62.4; p= 0.703). However, 12 months median VA change favoured TN cases (+4 TN vs +0 PT, p= 0.010) and median number of injections showed no differences (7 TN vs 7 PT, p= 0.644). No statistically significant differences were found at two years on number of injections even though mean final VA showed significant differences (66 TN vs 59.5 PT, p = 0.032) and VA change favoured the TN group (+2.4 TN vs - 4.6 PT, p= 0.003).Conclusion: We have successfully implemented an online tool to evaluate nAMD anti-VEGF treatment delivered in our center. This feasibility study demonstrates that the online audit tool allows evaluating real world intravitreal therapy outcomes and benchmark these results with clinical practice guidelines and other real-life series.


Ophthalmology ◽  
2014 ◽  
Vol 121 (10) ◽  
pp. 2073-2074 ◽  
Author(s):  
Daniel Barthelmes ◽  
Richard J. Walton ◽  
Jennifer J. Arnold ◽  
Ian L. McAllister ◽  
Judy M. Simpson ◽  
...  

2015 ◽  
Vol 09 (02) ◽  
pp. 157
Author(s):  
Richard P Gale ◽  
◽  
◽  
Reema Gupta

The management of neovascular age-related macular degeneration (nvAMD) has evolved significantly over the last few years with a significant step forward being taken with the advent of intravitreal therapy. Many different treatment regimens can be used, and the goal of treatment is shifting away from just salvaging vision to include reducing treatment burden on patients, carers and healthcare systems. This editorial discusses the common treatment regimens and proposes a pragmatic way of treating patients in three steps: (1) initiating a treatment, (2) finding the appropriate re-treatment interval and (3) fixing the re-treatment interval.


Ophthalmology ◽  
2015 ◽  
Vol 122 (6) ◽  
pp. 1212-1219 ◽  
Author(s):  
Jennifer J. Arnold ◽  
Anna Campain ◽  
Daniel Barthelmes ◽  
Judy M. Simpson ◽  
Robyn H. Guymer ◽  
...  

Retina ◽  
2018 ◽  
Vol 38 (1) ◽  
pp. 20-28 ◽  
Author(s):  
Daniel Barthelmes ◽  
Vuong Nguyen ◽  
Vincent Daien ◽  
Anna Campain ◽  
Richard Walton ◽  
...  

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