scholarly journals High-dose testosterone treatment reduces monoamine oxidase A levels in the human brain: a preliminary report

2021 ◽  
pp. 105381
Author(s):  
Georg S. Kranz ◽  
Marie Spies ◽  
Chrysoula Vraka ◽  
Ulrike Kaufmann ◽  
Eva-Maria Klebermass ◽  
...  
1980 ◽  
Vol 311 (3) ◽  
pp. 263-272 ◽  
Author(s):  
Christopher J. Fowler ◽  
Lars Oreland ◽  
Jan Marcusson ◽  
Bengt Winblad

2005 ◽  
Vol 26 (3) ◽  
pp. 330-344 ◽  
Author(s):  
Nathalie Ginovart ◽  
Jeffrey H Meyer ◽  
Anahita Boovariwala ◽  
Doug Hussey ◽  
Eugenii A Rabiner ◽  
...  

1989 ◽  
Vol 499 (1) ◽  
pp. 81-86 ◽  
Author(s):  
Johannes Kornhuber ◽  
Christine Konradi ◽  
Felizitas Mack-Burkhardt ◽  
Peter Riederer ◽  
Helmut Heinsen ◽  
...  

2013 ◽  
Vol 3 (1) ◽  
pp. 78 ◽  
Author(s):  
Paolo Zanotti-Fregonara ◽  
Claire Leroy ◽  
Dimitri Roumenov ◽  
Christian Trichard ◽  
Jean-Luc Martinot ◽  
...  

2014 ◽  
Vol 34 (12) ◽  
pp. 1951-1952 ◽  
Author(s):  
Paolo Zanotti-Fregonara ◽  
Michel Bottlaender

[11C]befloxatone is a positron emission tomography radioligand to image monoamine oxidase A (MAO-A) in the brain, which has been used in preclinical studies and in clinical protocols. However, a recent study found that [11C]befloxatone binding potential (k3/k4) has a poor correlation with MAO-A protein levels measured in the human brain. We here show that this poor correlation only depends on the choice of the parameter when performing kinetic modeling. In particular, the total volume of distribution of [11C]befloxatone shows a tight correlation with both protein and mRNA levels of MAO-A in the human brain.


2014 ◽  
Vol 35 (12) ◽  
pp. 1254-1261 ◽  
Author(s):  
Paolo Zanotti-Fregonara ◽  
Claire Leroy ◽  
Gaia Rizzo ◽  
Dimitri Roumenov ◽  
Christian Trichard ◽  
...  

Science ◽  
1987 ◽  
Vol 235 (4787) ◽  
pp. 481-485 ◽  
Author(s):  
J. Fowler ◽  
R. MacGregor ◽  
A. Wolf ◽  
C. Arnett ◽  
S. Dewey ◽  
...  

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