Sleep Positions in Children with Down Syndrome and Obstructive Sleep Apnea

2021 ◽  
Author(s):  
Jonathan D. Santoro ◽  
Justin Del Rosario ◽  
Beth Osterbauer ◽  
Emily S. Gillett ◽  
Debra M. Don
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Children With Down Syndrome ◽  
Obstructive Sleep

scholarly journals 0771 Severe Obstructive Sleep Apnea In Children With Down Syndrome

SLEEP ◽  
2018 ◽  
Vol 41 (suppl_1) ◽  
pp. A287-A287
Author(s):  
J N Mian ◽  
B Gunaratnam ◽  
E Senthilvel
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Severe Obstructive Sleep Apnea ◽  
Children With Down Syndrome ◽  
Obstructive Sleep

Obstructive Sleep Apnea in Children With Down Syndrome

PEDIATRICS ◽  
1991 ◽  
Vol 88 (1) ◽  
pp. 132-139
Author(s):  
Carole L. Marcus ◽  
Thomas G. Keens ◽  
Daisy B. Bautista ◽  
Walter S. von Pechmann ◽  
Sally L. Davidson Ward
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Arterial Oxygen Saturation ◽  
Sleep Apnea Syndrome ◽  
Arterial Oxygen ◽  
Children With Down Syndrome ◽  
Obstructive Sleep ◽  
Apnea Syndrome ◽  
End Tidal

Children with Down syndrome have many predisposing factors for the obstructive sleep apnea syndrome (OSAS), yet the type and severity of OSAS in this population has not been characterized. Fifty-three subjects with Down syndrome (mean age 7.4 ± 1.2 [SE] years; range 2 weeks to 51 years) were studied. Chest wall movement, heart rate, electrooculogram, end-tidal Po2 and Pco2, transcutaneous Po2 and Pco2, and arterial oxygen saturation were measured during a daytime nap polysomnogram. Sixteen of these children also underwent overnight polysomnography. Nap polysomnograms were abnormal in 77% of children; 45% had obstructive sleep apnea (OSA), 4% had central apnea, and 6% had mixed apneas; 66% had hypoventilation (end-tidal Pco2, >45 mm Hg) and 32% desaturation (arterial oxygen saturation <90%). Overnight studies were abnormal in 100% of children, with OSA in 63%, hypoventilation in 81%, and desaturation in 56%. Nap studies significantly underestimated the presence of abnormalities when compared to overnight polysomnograms. Seventeen (32%) of the children were referred for testing because OSAS was clinically suspected, but there was no clinical suspicion of OSAS in 36 (68%) children. Neither age, obesity, nor the presence of congenital heart disease affected the incidence of OSA, desaturation, or hypoventilation. Polysomnograms improved in all 8 children who underwent tonsilletomy and adenoidectomy, but they normalized in only 3. It is concluded that children with Down syndrome frequently have OSAS, with OSA, hypoxemia, and hypoventilation. Obstructive sleep apnea syndrome is seen frequently in those children in whom it is not clinically suspected. It is speculated that OSAS may contribute to the unexplained pulmonary hypertension seen in children with Down syndrome.

scholarly journals Does drug induced sleep endoscopy-directed surgery improve polysomnography measures in children with Down Syndrome and obstructive sleep apnea?

2018 ◽  
Vol 138 (11) ◽  
pp. 1009-1013 ◽  
Author(s):  
Sarah R. Akkina ◽  
Cheng C. Ma ◽  
Erin M. Kirkham ◽  
David L. Horn ◽  
Maida L. Chen ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Children With Down Syndrome ◽  
Drug Induced Sleep Endoscopy ◽  
Obstructive Sleep

scholarly journals 0879 Outcomes of Adenotonsillectomy in Children with Down Syndrome and Obstructive Sleep Apnea

SLEEP ◽  
2020 ◽  
Vol 43 (Supplement_1) ◽  
pp. A335-A335
Author(s):  
A Morello Gearhart ◽  
B Gunaratnam ◽  
E Senthilvel
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Sleep Onset ◽  
Sleep Efficiency ◽  
Apnea Hypopnea Index ◽  
P Value ◽  
Children With Down Syndrome ◽  
Arousal Index ◽  
Obstructive Sleep

Abstract Introduction Obstructive sleep apnea (OSA) is highly prevalent in children with Down Syndrome (DS). The aim of this study was to assess the effectiveness of adenotonsillectomy (T&A) on polysomnographic parameters of children with DS. Methods Retrospective chart review of children with DS who underwent T&A between 2012-2019 was performed. Preoperative OSA severity was categorized by obstructive apnea-hypopnea index (OAHI): mild = 1-4.9 events/h; moderate = 5-9.9 events/h; severe ≥ 10 events/h. Results We identified 43 DS children with pre and post T&A polysomnographic data in a population of 162 DS patients. A total of 25 were male, mean age 5.1 years (± 3.8 years) and 56% Caucasians. Preoperative data showed 19% mild OSA, 30% moderate and 51% severe. Postoperatively, apnea-hypopnea index (AHI) normalized in 9.3%, 37.2% had mild OSA, 18.6% moderate and 34.9% severe. Overall, T&A resulted in significant improvement (p-value <0.05) in mean AHI, (18.51 ± 28.05 vs 11.72 ± 16.43), SaO2 nadir (80.00 ± 14.82 vs 85.51 ± 5.94), sleep efficiency (81.97 ± 11.15 vs 85.9 ± 8.28), arousal index (16.14 ± 10.23 vs 14.45 ± 12.34), and wake after sleep onset (67.19 ± 46.89 vs 50.55 ± 40.83) and no statistical difference (p-value >0.05) in end-tidal carbon dioxide (43.86 ± 9.56 vs 44.17 ± 3.78), Rapid Eye Movement (REM)% (15.86 ± 7.75 vs 15.92 ± 7.41), sleep latency (24.03 ± 34.39 vs 22.55 ± 21.11), and central apnea index (0.86 ± 1.38 vs 0.66 ± 0.82) in pre and post T&A data. There was no statistically significant difference in pre and post T&A polysomnographic parameters between 17 DS and 17 age and gender-matched non-DS control subjects. Conclusion Adenotonsillectomy resulted in improvement in AHI, oxygen desaturation nadir, sleep efficiency, arousal index and wake after sleep onset. However, a significant portion of children with DS continued to have moderate to severe OSA after T&A. Support None.

scholarly journals 0719 Does Obstructive Sleep Apnea Affect Development in Children with Down Syndrome?

SLEEP ◽  
2019 ◽  
Vol 42 (Supplement_1) ◽  
pp. A288-A289
Author(s):  
Jillian Sanford ◽  
Elizabeth Super ◽  
Derek Lam ◽  
Joseph Pinter
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Children With Down Syndrome ◽  
Obstructive Sleep

Obstructive sleep apnea in younger school children with Down syndrome

2014 ◽  
Vol 78 (7) ◽  
pp. 1026-1029 ◽  
Author(s):  
Marit Erna Austeng ◽  
Britt Øverland ◽  
Kari Jorunn Kværner ◽  
Els-Marie Andersson ◽  
Stefan Axelsson ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
School Children ◽  
Children With Down Syndrome ◽  
Obstructive Sleep

Are home sleep studies useful in diagnosing obstructive sleep apnea in children with Down syndrome?

2017 ◽  
Author(s):  
Nilay Bas Ikizoglu ◽  
Esen Kiyan ◽  
Beldan Polat ◽  
Pinar Ay ◽  
Bulent Karadag ◽  
...  
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Children With Down Syndrome ◽  
Sleep Studies ◽  
Obstructive Sleep

Sleep problems and obstructive sleep apnea in children with down syndrome, an overview

2016 ◽  
Vol 82 ◽  
pp. 12-15 ◽  
Author(s):  
Mieke Maris ◽  
Stijn Verhulst ◽  
Marek Wojciechowski ◽  
Paul Van de Heyning ◽  
An Boudewyns
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Sleep Problems ◽  
Children With Down Syndrome ◽  
Obstructive Sleep

scholarly journals Prevalence of Obstructive Sleep Apnea in Children with Down Syndrome

SLEEP ◽  
2016 ◽  
Vol 39 (3) ◽  
pp. 699-704 ◽  
Author(s):  
Mieke Maris ◽  
Stijn Verhulst ◽  
Marek Wojciechowski ◽  
Paul Van de Heyning ◽  
An Boudewyns
Keyword(s):  
Obstructive Sleep Apnea ◽  
Down Syndrome ◽  
Sleep Apnea ◽  
Children With Down Syndrome ◽  
Obstructive Sleep
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