Molecular Characteristics of Biliary Tract and Primary Liver Tumors

2019 ◽  
Vol 28 (4) ◽  
pp. 685-693
Author(s):  
Susan Tsai ◽  
T. Clark Gamblin
Keyword(s):  
Biliary Tract ◽  
Liver Tumors ◽  
Molecular Characteristics ◽  
Primary Liver Tumors

scholarly journals Integrative Concepts for Liver Surgery

2020 ◽  
Vol 36 (5) ◽  
pp. 351-358
Author(s):  
Stefan Heinrich ◽  
Felix Watzka ◽  
Hauke Lang
Keyword(s):  
Liver Transplantation ◽  
Patient Selection ◽  
Liver Surgery ◽  
Liver Tumors ◽  
Treatment Options ◽  
Molecular Characteristics ◽  
Primary Tumors ◽  
Primary Liver Tumors ◽  
Liver Resections ◽  
Systemic Treatments

<b><i>Background:</i></b> Surgery is the standard treatment for primary tumors and metastases. Due to improvements in surgical outcomes as well as the efficacy of systemic treatments, the role of surgery has changed in recent years. <b><i>Summary:</i></b> Liver surgery has become safe and efficient, with resectability being increased by multimodality concepts as well as staged liver resections and orthotopic liver transplantation. These concepts may be applied to primary liver tumors but also to selected patients with liver metastases from various diseases. In addition, even debulking surgery may be indicated for selected patients with endocrine metastases. While patient selection for liver resections was limited to clinical parameters in the past, histological and molecular characteristics have become increasingly important. Moreover, the response to regional or systemic chemotherapy has been demonstrated to be strong for a beneficial course of the disease even in advanced diseases. <b><i>Key-Messages:</i></b> Due to the variety of available treatment options, optimal patient selection is crucial. Besides liver surgery, staged concepts as well as liver transplantation are curative tools for many patients.

Inoperable Biliary Tract and Primary Liver Tumors

2019 ◽  
Vol 28 (4) ◽  
pp. 745-762
Author(s):  
Sophia K. McKinley ◽  
Akhil Chawla ◽  
Cristina R. Ferrone
Keyword(s):  
Biliary Tract ◽  
Liver Tumors ◽  
Primary Liver Tumors

scholarly journals Staging of Biliary Tract and Primary Liver Tumors

2014 ◽  
Vol 23 (2) ◽  
pp. 313-322 ◽  
Author(s):  
Junichi Shindoh ◽  
Jean-Nicolas Vauthey
Keyword(s):  
Biliary Tract ◽  
Liver Tumors ◽  
Primary Liver Tumors
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