scholarly journals Modeling of TREX1-Dependent Autoimmune Disease using Human Stem Cells Highlights L1 Accumulation as a Source of Neuroinflammation

2017 ◽  
Vol 21 (3) ◽  
pp. 319-331.e8 ◽  
Author(s):  
Charles A. Thomas ◽  
Leon Tejwani ◽  
Cleber A. Trujillo ◽  
Priscilla D. Negraes ◽  
Roberto H. Herai ◽  
...  
2005 ◽  
Vol 35 (16) ◽  
pp. 14
Author(s):  
GUY McKHANN
Keyword(s):  

Author(s):  
A.A. Mikaelyan ◽  
◽  
N.L. Sheremet ◽  
A.Y. Andreev ◽  
A.A. Plyukhova ◽  
...  

2020 ◽  
Author(s):  
Giandomenico Turchiano ◽  
Geoffroy Andrieux ◽  
Georges Blattner ◽  
Valentina Pennucci ◽  
Julia Klermund ◽  
...  

Author(s):  
Diana B. Sequeira ◽  
Ana Rafaela Oliveira ◽  
Catarina M. Seabra ◽  
Paulo J. Palma ◽  
Carlos Ramos ◽  
...  

2020 ◽  
Vol 31 (23) ◽  
pp. 2583-2596
Author(s):  
John M. Boyle ◽  
Kelsey M. Hennick ◽  
Samuel G. Regalado ◽  
Jacob M. Vogan ◽  
Xiaozhu Zhang ◽  
...  

To better understand telomere length set point control in human stem cells, we generated knockout stem cell lines for TPP1 and contrasted their phenotypes with those of homozygous TPP1 L104A mutant stem cells. This comparison reveals that TPP1 L104A is not a hypomorphic allele but formally establishes TPP1 L104 as a dissociation of function mutant.


2015 ◽  
Vol 26 (2) ◽  
pp. S21
Author(s):  
Shing-Hwa Lu ◽  
Hsin-Chen Lee ◽  
Alex T.L. Lin ◽  
Kuang-Kuo Chen ◽  
Luke S. Chang

Theranostics ◽  
2017 ◽  
Vol 7 (18) ◽  
pp. 4591-4604 ◽  
Author(s):  
Kisuk Yang ◽  
Jin Young Oh ◽  
Jong Seung Lee ◽  
Yoonhee Jin ◽  
Gyeong-Eon Chang ◽  
...  
Keyword(s):  

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