Development of a general, enantioselective organocatalytic Mukaiyama–Michael reaction with α,β-unsaturated aldehydes

The inhibited iminium catalysis of the MDOs was switched on by using trans-cinnamic acid and the activated MDOs were used for catalyzing the domino Mannich condensation/Michael/Michael reaction between ketones and α,β-unsaturated aldehydes.

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Enantioselective organocatalytic Michael addition of isorhodanines to α,β-unsaturated aldehydes

Organic & Biomolecular Chemistry ◽

10.1039/c5ob02457a ◽

2016 ◽

Vol 14 (16) ◽

pp. 3926-3933 ◽

Cited By ~ 3

Author(s):

Shanchao Wu ◽

Yu Li ◽

Yongqiang Zhang ◽

Kun Fang ◽

Guoqiang Dong ◽

...

Keyword(s):

Secondary Amine ◽

Michael Addition ◽

Michael Reaction ◽

Catalytic Amount ◽

Unsaturated Aldehydes ◽

The Michael Reaction

The Michael reaction of substituted isorhodanines with α,β-unsaturated aldehydes in the presence of a catalytic amount of a chiral secondary amine is presented.

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ChemInform Abstract: Enantioselective Organocatalytic Phospha-Michael Reaction of α,β-Unsaturated Aldehydes.

ChemInform ◽

10.1002/chin.201206184 ◽

2012 ◽

Vol 43 (6) ◽

pp. no-no

Author(s):

Xiaoyan Luo ◽

Zhiqiang Zhou ◽

Xin Li ◽

Xinmiao Liang ◽

Jinxing Ye

Keyword(s):

Michael Reaction ◽

Unsaturated Aldehydes

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Direct Asymmetric Michael Reaction of α,β-Unsaturated Aldehydes and Ketones Catalyzed by Two Secondary Amine Catalysts

Angewandte Chemie International Edition ◽

10.1002/anie.201710085 ◽

2018 ◽

Vol 57 (7) ◽

pp. 1958-1962 ◽

Cited By ~ 17

Author(s):

Yujiro Hayashi ◽

Nariyoshi Umekubo

Keyword(s):

Secondary Amine ◽

Michael Reaction ◽

Unsaturated Aldehydes ◽

Aldehydes And Ketones ◽

Asymmetric Michael Reaction ◽

Amine Catalysts

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Innenrücktitelbild: Direct Asymmetric Michael Reaction of α,β-Unsaturated Aldehydes and Ketones Catalyzed by Two Secondary Amine Catalysts (Angew. Chem. 7/2018)

Angewandte Chemie ◽

10.1002/ange.201800065 ◽

2018 ◽

Vol 130 (7) ◽

pp. 2023-2023

Author(s):

Yujiro Hayashi ◽

Nariyoshi Umekubo

Keyword(s):

Secondary Amine ◽

Michael Reaction ◽

Unsaturated Aldehydes ◽

Aldehydes And Ketones ◽

Asymmetric Michael Reaction ◽

Amine Catalysts

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Development of a general, enantioselective organocatalytic Mukaiyama–Michael reaction with α,β-unsaturated aldehydes

Organocatalytic Enantioselective Aza-Michael Reaction of Nitrogen Heterocycles and α,β-Unsaturated Aldehydes.

Direct Asymmetric Michael Reaction of α,β-Unsaturated Aldehydes and Ketones Catalyzed by Two Secondary Amine Catalysts

Diphenylprolinol Silyl Ether as Catalyst of an Asymmetric, Catalytic, and Direct Michael Reaction of Nitroalkanes with α,β-Unsaturated Aldehydes

Diphenylprolinol Silyl Ether Catalyzed Asymmetric Michael Reaction of Nitroalkanes and β,β-Disubstituted α,β-Unsaturated Aldehydes for the Construction of All-Carbon Quaternary Stereogenic Centers

ChemInform Abstract: Development of a General Enantioselective Organocatalytic MukaiyamaâMichael Reaction with Î±,Î²-Unsaturated Aldehydes.

Diastereodivergent synthesis of 4-oxocyclohexanecarbaldehydes by using the modularly designed organocatalysts upon switching on their iminium catalysis

Enantioselective organocatalytic Michael addition of isorhodanines to α,β-unsaturated aldehydes

ChemInform Abstract: Enantioselective Organocatalytic Phospha-Michael Reaction of α,β-Unsaturated Aldehydes.

Direct Asymmetric Michael Reaction of α,β-Unsaturated Aldehydes and Ketones Catalyzed by Two Secondary Amine Catalysts

Innenrücktitelbild: Direct Asymmetric Michael Reaction of α,β-Unsaturated Aldehydes and Ketones Catalyzed by Two Secondary Amine Catalysts (Angew. Chem. 7/2018)

ChemInform Abstract: Development of a General Enantioselective Organocatalytic MukaiyamaâMichael Reaction with Î±,Î²-Unsaturated Aldehydes.