Ascorbic acid specifically reduces the misclassification of nonirritating reactive chemicals in the OptiSafe™ macromolecular eye irritation test

2022 ◽  
pp. 105313
Author(s):  
StewartJ. Lebrun ◽  
Sara Chavez ◽  
Roxanne Chan ◽  
Linda Nguyen ◽  
James V. Jester
Keyword(s):  
Ascorbic Acid ◽  
Eye Irritation ◽  
Reactive Chemicals ◽  
Irritation Test

A Collaborative Evaluation of Seven Alternatives to the Draize Eye Irritation Test Using Pharmaceutical Intermediates

1995 ◽  
Vol 26 (1) ◽  
pp. 20-31
Author(s):  
J. F. SINA ◽  
D. M. GALER ◽  
R. G. SUSSMAN ◽  
P. D. GAUTHERON ◽  
E. V. SARGENT ◽  
...  
Keyword(s):  
Eye Irritation ◽  
Irritation Test ◽  
Collaborative Evaluation

Evaluation of the EpiOcularTM Tissue Model as an Alternative to the Draize Eye Irritation Test

1998 ◽  
Vol 12 (4) ◽  
pp. 455-461 ◽  
Author(s):  
M. Stern ◽  
M. Klausner ◽  
R. Alvarado ◽  
K. Renskers ◽  
M. Dickens
Keyword(s):  
Eye Irritation ◽  
Tissue Model ◽  
Irritation Test

The CTFA evaluation of alternatives program: An evaluation of in vitro alternatives to the draize primary eye irritation test. (Phase II) oil/water emulsions

1994 ◽  
Vol 32 (10) ◽  
pp. 943-976 ◽  
Author(s):  
S.D. Gettings ◽  
L.C. Dipasquale ◽  
D.M. Bagley ◽  
P.L. Casterton ◽  
M. Chudkowski ◽  
...  
Keyword(s):  
Phase Ii ◽  
Test Phase ◽  
Eye Irritation ◽  
Irritation Test ◽  
Oil Water

Correlation and validation of alternative methods to the Draize eye irritation test (OPAL project)

1991 ◽  
Vol 5 (5-6) ◽  
pp. 555-557 ◽  
Author(s):  
O. Blein ◽  
M. Adolphe ◽  
B. Lakhdar ◽  
J. Cambar ◽  
G. Gubanski ◽  
...  
Keyword(s):  
Alternative Methods ◽  
Eye Irritation ◽  
Irritation Test

[3H]-Arachidonic Acid Release as an Alternative to the Eye Irritation Test

1995 ◽  
pp. 255-261 ◽  
Author(s):  
Hans-Peter Klöcking ◽  
Ulf Schlegelmilch ◽  
Renate Klöcking
Keyword(s):  
Arachidonic Acid ◽  
Arachidonic Acid Release ◽  
Eye Irritation ◽  
Irritation Test ◽  
Acid Release

Me-too validation study for in vitro eye irritation test with 3D-reconstructed human cornea epithelium, MCTT HCETM

2019 ◽  
Vol 55 ◽  
pp. 173-184 ◽  
Author(s):  
Song-E Lim ◽  
Su Jin Ha ◽  
Won-Hee Jang ◽  
Kyung-Mi Jung ◽  
Mi-Sook Jung ◽  
...  
Keyword(s):  
Validation Study ◽  
Human Cornea ◽  
Eye Irritation ◽  
Irritation Test ◽  
Cornea Epithelium
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