Islet transplantation in type 1 diabetic patients

2004 ◽  
Vol 36 (3) ◽  
pp. 603-604 ◽  
Author(s):  
F. Bertuzzi ◽  
A. Secchi ◽  
V.Di Carlo
2017 ◽  
Author(s):  
Federica Ermetici ◽  
Silvia Briganti ◽  
Stefano Benedini ◽  
Roberto Codella ◽  
Paola Maffi ◽  
...  

2003 ◽  
Vol 16 (3) ◽  
pp. 186-190 ◽  
Author(s):  
Babak Movahedi ◽  
Bart Keymeulen ◽  
Mary-Helen Lauwers ◽  
Eva Goes ◽  
Nadine Cools ◽  
...  

1991 ◽  
Vol 28 (2) ◽  
pp. 151-157 ◽  
Author(s):  
C. Socci ◽  
L. Falqui ◽  
A. M. Davalli ◽  
C. Ricordi ◽  
S. Braghi ◽  
...  

2004 ◽  
Vol 36 (9) ◽  
pp. 2869-2873 ◽  
Author(s):  
P.B. Djordjevic ◽  
N.M. Lalic ◽  
A. Jotic ◽  
I. Paunovic ◽  
K. Lalic ◽  
...  

2000 ◽  
Vol 69 (Supplement) ◽  
pp. S400 ◽  
Author(s):  
A. M.James Shapiro ◽  
Jonathan R.T. Lakey ◽  
Edmond Ryan ◽  
Gregory S. Korbutt ◽  
Ellen Toth ◽  
...  

2003 ◽  
Vol 76 (Supplement) ◽  
pp. S47
Author(s):  
M C Vantyghem ◽  
P Perimenis ◽  
S Tourvieille ◽  
B Soudan ◽  
F Pattou

2020 ◽  
Vol 29 ◽  
pp. 096368972095234
Author(s):  
M. Rezaa Mohammadi ◽  
Farideh Dehkordi-Vakil ◽  
Joni Ricks-Oddie ◽  
Robert Mansfield ◽  
Himala Kashimiri ◽  
...  

Transplantation of pancreatic islets within a biomaterial device is currently under investigation in clinical trials for the treatment of patients with type 1 diabetes (T1D). Patients’ preferences on such implants could guide the designs of next-generation implantable devices; however, such information is not currently available. We surveyed the preferences of 482 patients with T1D on the size, shape, visibility, and transplantation site of islet containing implants. More than 83% of participants were willing to receive autologous stem cells, and there was no significant association between implant fabricated by one’s own stem cell with gender ( χ 2 (1, n = 468) = 0.28; P = 0.6) or with age ( χ 2 (4, n = 468) = 2.92; P = 0.6). Preferred location for islet transplantation within devices was under the skin (52.7%). 48.3% preferred microscopic disks, and 32.3% preferred a thin device (like a credit card). Moreover, 58.4% preferred the implant to be as small as possible, 25.4% did not care about visibility, and 16.2% preferred their implants not to be visible. Among female participants, 81% cared about the implant visibility, whereas this number was 64% for male respondents ( χ 2 test (1, n = 468) = 16.34; P < 0.0001). 22% of those younger than 50 years of age and 30% of those older than 50 did not care about the visibility of implant ( χ 2 test (4, n = 468) = 23.69; P < 0.0001). These results suggest that subcutaneous sites and micron-sized devices are preferred choices among patients with T1D who participated in our survey.


Sign in / Sign up

Export Citation Format

Share Document