Construction and characterization of a replication-competent human adenovirus type 3-based vector as a live-vaccine candidate and a viral delivery vector

Vaccine ◽  
2009 ◽  
Vol 27 (8) ◽  
pp. 1145-1153 ◽  
Author(s):  
Qiwei Zhang ◽  
Xiaobo Su ◽  
Donald Seto ◽  
Bo-jian Zheng ◽  
Xingui Tian ◽  
...  
Keyword(s):  
Vaccine Candidate ◽  
Human Adenovirus ◽  
Adenovirus Type ◽  
Live Vaccine ◽  
Delivery Vector ◽  
Type 3

A recombinant replication-defective human adenovirus type 3: A vaccine candidate

Vaccine ◽  
2009 ◽  
Vol 27 (1) ◽  
pp. 116-122 ◽  
Author(s):  
Haitao Li ◽  
Rong Zhou ◽  
Jingxian Chen ◽  
Xingui Tian ◽  
Qiwei Zhang ◽  
...  
Keyword(s):  
Vaccine Candidate ◽  
Human Adenovirus ◽  
Adenovirus Type ◽  
Type 3

Construction and characterization of a recombinant human adenovirus type 3 vector containing two foreign neutralizing epitopes in hexon

2014 ◽  
Vol 183 ◽  
pp. 67-74 ◽  
Author(s):  
Chunyan Xue ◽  
Xingui Tian ◽  
Xiao Li ◽  
Zhichao Zhou ◽  
Xiaobo Su ◽  
...  
Keyword(s):  
Human Adenovirus ◽  
Adenovirus Type ◽  
Type 3 ◽  
Neutralizing Epitopes

Epitope mapping and characterization of a neutralizing monoclonal antibody against human adenovirus type 3

2013 ◽  
Vol 177 (2) ◽  
pp. 189-193 ◽  
Author(s):  
Xingui Tian ◽  
Chenyang Li ◽  
Chunyan Xue ◽  
Xiao Li ◽  
Zhichao Zhou ◽  
...  
Keyword(s):  
Monoclonal Antibody ◽  
Epitope Mapping ◽  
Human Adenovirus ◽  
Adenovirus Type ◽  
Neutralizing Monoclonal Antibody ◽  
Type 3

Characterization of malleability and immunological properties of human adenovirus type 3 hexon hypervariable region 1

2012 ◽  
Vol 157 (9) ◽  
pp. 1709-1718 ◽  
Author(s):  
Tianhua Zhong ◽  
Xiao Li ◽  
Zhichao Zhou ◽  
Ting Li ◽  
Xingui Tian ◽  
...  
Keyword(s):  
Hypervariable Region ◽  
Human Adenovirus ◽  
Adenovirus Type ◽  
Immunological Properties ◽  
Hypervariable Region 1 ◽  
Type 3

The penton base of human adenovirus type 3 has the RGD motif

Gene ◽  
1994 ◽  
Vol 146 (2) ◽  
pp. 257-259 ◽  
Author(s):  
Alain Cuzange ◽  
Jadwiga Chroboczek ◽  
Bernard Jacrot
Keyword(s):  
Human Adenovirus ◽  
Adenovirus Type ◽  
Penton Base ◽  
Rgd Motif ◽  
Type 3

scholarly journals Sequence of the human adenovirus type 3 protease

1988 ◽  
Vol 16 (23) ◽  
pp. 11374-11374 ◽  
Author(s):  
Alain Houde ◽  
Joseph M. Weber
Keyword(s):  
Human Adenovirus ◽  
Adenovirus Type ◽  
Type 3

scholarly journals Chimpanzee adenovirus CV-68 adapted as a gene delivery vector interacts with the coxsackievirus and adenovirus receptor

2002 ◽  
Vol 83 (1) ◽  
pp. 151-155 ◽  
Author(s):  
Christopher J. Cohen ◽  
Zhi Quan Xiang ◽  
Guang-Ping Gao ◽  
Hildegund C. J. Ertl ◽  
James M. Wilson ◽  
...  
Keyword(s):  
Gene Delivery ◽  
Cho Cells ◽  
Human Adenovirus ◽  
Adenovirus Type ◽  
Soluble Form ◽  
Delivery Vector ◽  
Coxsackievirus And Adenovirus Receptor ◽  
Adenovirus Receptor ◽  
Adenovirus Type 5 ◽  
Dependent Mechanism

A replication-defective form of chimpanzee adenovirus type 68 (C68) has been developed to circumvent problems posed by widespread preexisting immunity to common human adenovirus vectors. To investigate the determinants of C68 tropism, its interaction with the coxsackievirus and adenovirus receptor (CAR) was studied. Although CHO cells were resistant to transduction by C68 as well as by adenovirus type 5 (Ad5), CHO cells expressing either human or murine CAR were transduced readily. C68 transduction, like Ad5 transduction, was blocked when cells were exposed to anti-CAR antibody or when virus was exposed to a soluble form of the CAR extracellular domain. These results indicate that gene delivery by C68 occurs by a CAR-dependent mechanism.

Isolation and characterization of adenovirus-associated VA RNAs of human adenovirus type 7

Gene ◽  
1994 ◽  
Vol 142 (2) ◽  
pp. 309-310
Author(s):  
Pei Pei Smith ◽  
Surendra Dheer ◽  
Alan Davis ◽  
Paul P. Hung ◽  
Shaw-Guang Lee
Keyword(s):  
Human Adenovirus ◽  
Adenovirus Type ◽  
Isolation And Characterization
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