Two decades of hepatitis B vaccination in mentally retarded patients: Effectiveness, antibody persistence and duration of immune memory

Vaccine ◽  
2012 ◽  
Vol 30 (32) ◽  
pp. 4757-4761 ◽  
Author(s):  
Tessa Braeckman ◽  
Koen Van Herck ◽  
Wolfgang Jilg ◽  
Tanja Bauer ◽  
Pierre Van Damme
Keyword(s):  
Hepatitis B ◽  
Mentally Retarded ◽  
Immune Memory ◽  
Hepatitis B Vaccination ◽  
Antibody Persistence

scholarly journals Cross-Protection of Hepatitis B Vaccination among Different Genotypes

Vaccines ◽  
2020 ◽  
Vol 8 (3) ◽  
pp. 456
Author(s):  
Takako Inoue ◽  
Yasuhito Tanaka
Keyword(s):  
Hepatitis B ◽  
Cross Protection ◽  
Hbv Infection ◽  
Immune Memory ◽  
Hepatitis B Vaccination ◽  
Infection Model ◽  
Hbv Genotype ◽  
Hb Vaccine ◽  
Genotype A

Hepatitis B (HB) vaccination is the most effective method for preventing HB virus (HBV) infection. Universal HB vaccination containing recombinant HB surface antigens (HBsAg) is recommended. Our data revealed that human monoclonal HB surface antibody (anti-HBs) from individuals inoculated with genotype C-based HB vaccine induced cross-protection against HBV genotype A infection. An in vitro infection model demonstrated anti-HBs-positive sera from individuals inoculated with genotype A- or C-based HB vaccine harbored polyclonal anti-HBs that could bind to non-vaccinated genotype HBV. However, because there were low titers of anti-HBs specific for HBsAg of non-vaccinated genotype, high anti-HBs titers would be required to prevent non-vaccinated genotype HBV infection. Clinically, the 2015 Centers for Disease Control and Prevention guidelines state that periodic monitoring of anti-HBs levels after routine HB vaccination is not needed and that booster doses of HB vaccine are not recommended. However, the American Red Cross suggests that HB-vaccine-induced immune memory might be limited; although HB vaccination can prevent clinical liver injury (hepatitis), subclinical HBV infections of non-vaccinated genotypes resulting in detectable HB core antibody could not be completely prevented. Therefore, monitoring anti-HBs levels after routine vaccination might be necessary for certain subjects in high-risk groups.

scholarly journals Persistence of HB sAg‐specific antibodies and immune memory two to three decades after hepatitis B vaccination in adults

2019 ◽  
Vol 26 (9) ◽  
pp. 1066-1075 ◽  
Author(s):  
Pierre Van Damme ◽  
Marc Dionne ◽  
Geert Leroux‐Roels ◽  
Olivier Van Der Meeren ◽  
Emmanuel Di Paolo ◽  
...  
Keyword(s):  
Hepatitis B ◽  
Immune Memory ◽  
Hepatitis B Vaccination ◽  
Specific Antibodies

Duration of immunity to hepatitis B vaccination in institutionalized mentally retarded patients

Vaccine ◽  
1989 ◽  
Vol 7 (2) ◽  
pp. 102-103 ◽  
Author(s):  
Donato Torre ◽  
Marco Broggini ◽  
Vanna Botta ◽  
Carmen Sampietro
Keyword(s):  
Hepatitis B ◽  
Mentally Retarded ◽  
Hepatitis B Vaccination

scholarly journals Determination of immune memory to hepatitis B vaccination through early booster response in college students

Hepatology ◽  
2010 ◽  
Vol 51 (5) ◽  
pp. 1547-1554 ◽  
Author(s):  
Chyi-Feng Jan ◽  
Kuo-Chin Huang ◽  
Yin-Chu Chien ◽  
Donald E. Greydanus ◽  
H. Dele Davies ◽  
...  
Keyword(s):  
College Students ◽  
Hepatitis B ◽  
Immune Memory ◽  
Hepatitis B Vaccination

scholarly journals Characteristics of immune memory 10–15 years after primary hepatitis B vaccination

Vaccine ◽  
2016 ◽  
Vol 34 (5) ◽  
pp. 636-642 ◽  
Author(s):  
Irena Brunskole Hummel ◽  
Anita Zitzmann ◽  
Monika Erl ◽  
Jürgen J. Wenzel ◽  
Wolfgang Jilg
Keyword(s):  
Hepatitis B ◽  
Immune Memory ◽  
Hepatitis B Vaccination
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