Primary angioplasty with routine stenting compared with thrombolytic therapy in elderly patients with acute myocardial infarction

2003 ◽  
Vol 145 (5) ◽  
pp. 862-867 ◽  
Author(s):  
Ilan Goldenberg ◽  
Shlomi Matetzky ◽  
Amir Halkin ◽  
Arie Roth ◽  
Elio Di Segni ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Elderly Patients ◽  
Thrombolytic Therapy ◽  
Primary Angioplasty

scholarly journals Primary Angioplasty for Acute Myocardial Infarction

1997 ◽  
Vol 2 (4) ◽  
pp. 327-334 ◽  
Author(s):  
Craig P Juergens ◽  
Robert J Whitbourn ◽  
Alan C Yeung ◽  
Stephen N Oesterle
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Significant Risk ◽  
Hospital Setting ◽  
Reperfusion Therapy ◽  
Primary Angioplasty ◽  
Coronary Perfusion ◽  
Short Term Mortality ◽  
Reperfusion Strategy

The use of thrombolytic therapy has been widely accepted for the treatment of acute myocardial infarction. Despite improving mortality, thrombolytic therapy may be contraindicated in many patients presenting with myocardial infarction and is associated with a small, yet significant risk of hemorrhagic sequelae. This article outlines the rationale behind reperfusion therapy, the use of pharmacological thrombolysis and the role of adjunctive angioplasty. The potential advantages of a therapeutic strategy of primary angioplasty, instead of thrombolysis, are discussed. These include anatomical definition, risk stratification, reduced recurrent ischemia, enhanced coronary perfusion and improved coronary patency. The randomized trials in which primary angioplasty and thrombolytic therapy were compared are reviewed. We conclude that angioplasty results in a reduction of short-term mortality and nonfatal reinfarction and therefore advocate the routine use of coronary angioplasty as a primary reperfusion strategy for acute myocardial infarction. The potential limitations of primary angioplasty in the community hospital setting are discussed. Finally, we examine the roles of adjunctive mechanical (e.g. stents) and pharmacological (e.g. Abciximab) means of further enhancing outcomes after primary angioplasty.

Comparison of primary angioplasty versus thrombolytic therapy for acute myocardial infarction

1994 ◽  
Vol 74 (2) ◽  
pp. 111-118 ◽  
Author(s):  
William J. Rogers ◽  
◽  
Larry S. Dean ◽  
Paul B. Moore ◽  
Kenneth J. Wool ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Thrombolytic Therapy ◽  
Primary Angioplasty

Improvement in Long-term Prognosis of Elderly Patients with Acute Myocardial Infarction After the Introduction of Intravenous Thrombolytic Therapy

1998 ◽  
Vol 32 (6) ◽  
pp. 365-370 ◽  
Author(s):  
Johnny Madsen Koerstz ◽  
Pedersen Flemming ◽  
Henrik Nielsen ◽  
Gunnar Vagn ◽  
Fischer Hansen Jensen Jørgen
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Elderly Patients ◽  
Thrombolytic Therapy ◽  
Long Term Prognosis

Thrombolytic therapy for eligible elderly patients with acute myocardial infarction

2005 ◽  
Vol 149 (5) ◽  
pp. e25-e26 ◽  
Author(s):  
Syed Wamique Yusuf ◽  
Kathy A. McLean ◽  
Radha A. Mishra
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Elderly Patients ◽  
Thrombolytic Therapy

An active lifestyle improves outcome of primary angioplasty in elderly patients with acute myocardial infarction

2007 ◽  
Vol 154 (2) ◽  
pp. 352-360 ◽  
Author(s):  
Giuseppe Rengo ◽  
Gennaro Galasso ◽  
Federico Piscione ◽  
Luca Golino ◽  
Francesca Fortunato ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Elderly Patients ◽  
Primary Angioplasty ◽  
Active Lifestyle

scholarly journals A Study of the Efficacy of Thrombolytic Therapy for Acute Myocardial Infarction in Elderly Patients.

1995 ◽  
Vol 32 (7) ◽  
pp. 478-484
Author(s):  
Toshiya Muramatsu ◽  
Yoshimasa Yabe ◽  
Hajime Nakano ◽  
Kenji Wagatsuma ◽  
Toshihiko Uchida
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Elderly Patients ◽  
Thrombolytic Therapy
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