Increassed parietal cell density in patients with perfurated duodenal ulcer: Comparison with non-complicated duodenal ulcer patients

2001 ◽  
Vol 120 (5) ◽  
pp. A250-A250
Author(s):  
A BARBOSA ◽  
C MENDES ◽  
L COELHO ◽  
C RODRIGUES ◽  
M MACHADO ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Cell Density ◽  
Parietal Cell

Increassed parietal cell density in patients with perfurated duodenal ulcer: Comparison with non-complicated duodenal ulcer patients

2001 ◽  
Vol 120 (5) ◽  
pp. A250 ◽  
Author(s):  
Alfredo J.A. Barbosa ◽  
Claudia M.C. Mendes ◽  
Luiz G.V. Coelho ◽  
Carolinne B. Rodrigues ◽  
Mariana M.L. Machado ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Cell Density ◽  
Parietal Cell

Parietal cell vagotomy for intractable and obstructing duodenal ulcer

1981 ◽  
Vol 141 (4) ◽  
pp. 482-486 ◽  
Author(s):  
Ricardo L. Rossi ◽  
John W. Braasch ◽  
Blake Cady ◽  
Cornelius E. Sedgwick
Keyword(s):  
Duodenal Ulcer ◽  
Parietal Cell ◽  
Parietal Cell Vagotomy

scholarly journals Serial Studies of Gastric Secretion in Patients After Highly Selective (Parietal Cell) Vagotomy without a Drainage Procedure for Duodenal Ulcer

1973 ◽  
Vol 64 (1) ◽  
pp. 1-11 ◽  
Author(s):  
D. Johnston ◽  
A.R. Wilkinson ◽  
C.S. Humphrey ◽  
R.B. Smith ◽  
J.C. Goligher ◽  
...  
Keyword(s):  
Duodenal Ulcer ◽  
Gastric Secretion ◽  
Parietal Cell ◽  
Drainage Procedure ◽  
Parietal Cell Vagotomy

scholarly journals Parietal cell responsiveness in duodenal ulcer.

BMJ ◽  
1967 ◽  
Vol 1 (5535) ◽  
pp. 278-278 ◽  
Author(s):  
K. G. Wormsley ◽  
M. P. Mahoney
Keyword(s):  
Duodenal Ulcer ◽  
Parietal Cell

Gastrin mediates the increase in gastric cell growth in uremic rats

1995 ◽  
Vol 268 (4) ◽  
pp. G586-G591 ◽  
Author(s):  
E. Quintero ◽  
G. V. Ohning ◽  
M. Del Rivero ◽  
H. C. Wong ◽  
J. H. Walsh ◽  
...  
Keyword(s):  
Gastric Mucosa ◽  
Cell Density ◽  
Parietal Cell ◽  
Rat Model ◽  
Chronic Administration ◽  
Mucosal Blood Flow ◽  
Gastric Mucosal Blood Flow ◽  
Arterial Blood ◽  
Ecl Cell ◽  
Stomach Weight

In a rat model of chronic renal failure, we recently reported that hypergastrinemia was associated with increased stomach weight and parietal cell and enterochromaffin-like (ECL) cell density. In this study, the role of gastrin in mediating trophic effects of uremia on the gastric mucosa was examined by chronic immunoneutralization of endogenous gastrin in the sub-total nephrectomy uremic rat model. Three weeks after surgery, the rats were uremic (azotemic and hypertensive). Uremic rats had a significant increase in corpus mucosal height (17%), parietal cell density (14%), ECL cell density (27%), and basal gastric mucosal blood flow (63%). These effects were specifically inhibited by chronic administration of gastrin-specific monoclonal antibody (5 mg ip every other day) in the 3-wk postoperative period. Uremic rats also had an increase in stomach weight (23%), corpus mucosal area (8%), arterial blood pressure, and serum creatinine and a decrease in body weight. Gastrin immunoneutralization did not alter these effects. The findings suggest that elevated levels of endogenous circulating gastrin in uremic rats mediate, in part, the trophic response observed in the gastric mucosa.

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