Sa1308 Extended Bravo Studies (>48 hrs) offer an Additional Diagnostic Yield of Gastro-Esophageal Reflux Disease (GERD) in Patients With Normal Multichannel Intraluminal Impedance-pH (MII-pH) Studies

2016 ◽  
Vol 150 (4) ◽  
pp. S277-S278
Author(s):  
Christopher T. Chia ◽  
Ismail Miah ◽  
Jafar Jafari ◽  
Ioannis Koumoutsos ◽  
Ikram Nasr ◽  
...  
Keyword(s):  
Reflux Disease ◽  
Diagnostic Yield ◽  
Esophageal Reflux ◽  
Multichannel Intraluminal Impedance ◽  
Intraluminal Impedance ◽  
Multichannel Intraluminal Impedance Ph

scholarly journals Validation of Peptest™ in Patients with Gastro-Esophageal Reflux Disease and Laryngopharyngeal Reflux Undergoing Impedance Testing

2019 ◽  
Vol 28 (4) ◽  
pp. 383-387 ◽  
Author(s):  
Serhat Bor ◽  
Doga Capanoglu ◽  
Rukiye Vardar ◽  
Andrew D Woodcock ◽  
Jeanine Fisher ◽  
...  
Keyword(s):  
Reflux Disease ◽  
Laryngopharyngeal Reflux ◽  
Esophageal Reflux ◽  
First Line ◽  
Multichannel Intraluminal Impedance ◽  
Intraluminal Impedance ◽  
Reflux Event ◽  
In Vitro Diagnostic ◽  
Impedance Testing

Background and Aims: Pepsin in the gastric refluxate is a marker for a prior reflux event and rapid detection might be achieved using the Peptest™, an in vitro diagnostic medical device. The aim of this study was to validate the use of Peptest™ to reliably diagnose reflux in patients with gastro-esophageal reflux disease (GERD) and laryngopharyngeal reflux (LPR) disease diagnosed with multichannel intraluminal impedance/ pHmetry (MII-pH). Methods: 20 reflux patients were recruited of whom 10 had classical GERD and 10 had LPR. All patients underwent MII-pH and provided expectorated saliva samples when a MII-pH reflux event was observed, or reflux symptoms were experienced, and all were tested for the presence of pepsin using the Peptest™. Results: Pepsin was detected in 31 out of 45 samples (68.9%). At least 1 positive pepsin result was seen in 16 patients (80%) and this was the same, irrespective of the GERD or LPR diagnosis. Peptest™ had a positive predictive value of 69% to detect MII-pH reflux events. Conclusions: Peptest™ is a good first-line diagnostic procedure to use in reflux sufferers to confirm the presence of reflux.

The utility of multichannel intraluminal impedance‐pH testing in tailoring the management of paediatric gastro‐oesophageal reflux disease

2020 ◽  
Vol 109 (12) ◽  
pp. 2799-2807
Author(s):  
Hema Lattha Gunasagaran ◽  
Vincent Varjavandi ◽  
Daniel A. Lemberg ◽  
Chee Y. Ooi ◽  
Nitin Gupta ◽  
...  
Keyword(s):  
Reflux Disease ◽  
Oesophageal Reflux ◽  
Multichannel Intraluminal Impedance ◽  
Oesophageal Reflux Disease ◽  
Intraluminal Impedance ◽  
Multichannel Intraluminal Impedance Ph
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