Initial experience of videocapsule endoscopy for diagnosing small-bowel tumors in patients with GI polyposis syndromes

Abstract Background. Capsule endoscopy is a revolutionary new diagnostic method for the detection of digestive diseases, especially localized at the level of small bowel and colorectal tract. This method is the only technique that allows endoscopic examination of the digestive tract without sedation. Obscure gastrointestinal bleeding is the most common indication for capsule endoscopy, which commonly diagnoses arteriovenous malformations, small bowel tumors, ulcers or tumors missed at standard endoscopy or other imaging examinations [1]. Aim. Our study aimed to detect the accuracy of endoscopic videocapsule in detecting the cause of microscopic anemia in patients with supposed digestive pathologies. Material and method. We used PillCam 2 Platform provided by Given Imaging, a system consisting of PillCam 2 videocapsules, a data recorder, a set of sensors and the Rapid 7 Access computer soft capable to receive and transform pictures into films, in order to visualize the entire digestive gastrointestinal tract. We examined 25 patients with chronic anemia, all of them without any known hematologic, renal or digestive disease, investigated by standard imagistic and lab techniques. Results. From the total of 25 investigated patients, 18 (72%) of them presented sources of bleeding discovered with videocapsule endoscopy. The source of bleeding was the small bowel in 10 cases (55%) and the colorectal tract in 8 cases (45%). The accuracy of videocapsule was very good for detecting the digestive tract obscure sources of bleeding (Sn=74%, Sp=87%). Conclusions. The videocapsule endoscopy is an accurate imagistic option to detect digestive sources of bleeding and to identify the cause of many chronic anemia

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Small Bowel Tumors and Polyposis Syndromes

Gastrointestinal Endoscopy Clinics of North America ◽

10.1016/s1052-5157(18)30222-8 ◽

1999 ◽

Vol 9 (1) ◽

pp. 93-114 ◽

Cited By ~ 33

Author(s):

Francesco P. Rossini ◽

Mauro Risio ◽

Marco Pennazio

Keyword(s):

Small Bowel ◽

Small Bowel Tumors ◽

Polyposis Syndromes

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Intussusception in Adults with Small Bowel Tumors

Gastroenterology ◽

10.1016/s0016-5085(49)80039-4 ◽

1949 ◽

Vol 12 (2) ◽

pp. 290-301

Author(s):

Robert M. Lowman ◽

William Mendelsohn

Keyword(s):

Small Bowel ◽

Small Bowel Tumors

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Initial experience of wireless-capsule endoscopy for evaluating occult gastrointestinal bleeding and suspected small bowel pathology

The American Journal of Gastroenterology ◽

10.1111/j.1572-0241.2002.07021.x ◽

2002 ◽

Vol 97 (11) ◽

pp. 2776-2779 ◽

Cited By ~ 188

Author(s):

Eitan Scapa ◽

Harold Jacob ◽

Shlomo Lewkowicz ◽

Michal Migdal ◽

Daniel Gat ◽

...

Keyword(s):

Small Bowel ◽

Gastrointestinal Bleeding ◽

Capsule Endoscopy ◽

Wireless Capsule Endoscopy ◽

Initial Experience ◽

Occult Gastrointestinal Bleeding ◽

Wireless Capsule

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Small Intestine: Neuroendocrine and Miscellaneous Tumors

10.2310/cgso.16093 ◽

2017 ◽

Author(s):

Joel M Baumgartner ◽

Sudeep Banerjee ◽

Jason K Sicklick

Keyword(s):

Small Intestine ◽

Small Bowel ◽

Surgical Intervention ◽

Distant Metastases ◽

Somatostatin Analogues ◽

Locoregional Therapy ◽

Small Bowel Tumors ◽

Small Bowel Tumor ◽

Key Words Carcinoid Tumor ◽

A Site

Carcinoid tumors are the most common nonduodenal small bowel tumors. Although the diagnosis of any small bowel tumor is challenging, serum tumor markers and specialized imaging can aid in the diagnosis of carcinoid. Localized carcinoids are treated with surgical resection, whereas metastatic tumors are treated with somatostatin analogues, although liver-directed therapies can improve disease-related symptoms. In contrast, small bowel lymphomas are primarily treated with chemotherapy and sometimes radiation, although surgical intervention may be necessary for diagnosis and resection for palliation of symptoms. Furthermore, there are many benign etiologies of small bowel tumors, including adenoma, leiomyoma, and lipoma. The small bowel can also be a site of distant metastases for which surgical management is reserved for the treatment of complications such as bleeding, obstruction, perforation, or pain. This review contains 3 figures, 3 tables and 17 references. Key words: carcinoid tumor, desmoid tumor, locoregional therapy, mesentery, neuroendocrine tumor, small bowel, small bowel lymphoma, somatostatin

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Duodenal Malignancies

10.2310/7800.16072 ◽

2018 ◽

Author(s):

Emily R Newton ◽

Benjamin H Schmidt ◽

Michael O Meyers

Keyword(s):

Small Bowel ◽

Primary Treatment ◽

Carcinoid Tumors ◽

Adjunctive Treatment ◽

Small Bowel Tumors ◽

Cross Sectional ◽

Carcinoid Crisis ◽

Cross Sectional Imaging ◽

Duodenal Carcinoma ◽

Duodenal Resection

Although malignancies involving the small bowel are rare, one-third of these are located in the duodenum. The majority of duodenal tumors are adenocarcinoma but also may include gastrointestinal stromal tumors (GIST), carcinoid or neuroendocrine tumors, sarcomas, and lymphoma. These commonly present with nonspecific symptoms, but obstructive patterns predominate when symptoms are present. Preoperative diagnosis is made via endoscopy and/or cross-sectional imaging. This section focuses on treatment and surgical management for adenocarcinoma, carcinoid tumors, and GISTs of the duodenum. Surgical resection is the primary treatment of for all three of these, but all have significant nuances in surgical planning and decision-making as well as variability in the role of adjunctive treatment in their management. Functional carcinoid tumors can have hormone-driven symptoms and are associated with an increase in risk of carcinoid crisis, which may be prophylactically treated with intravenous octreotide. Resection of these tumors relies heavily on tumor relationship to the ampulla. Key anatomic distinctions and clinical tips to identify the ampulla to ensure an appropriate duodenal resection are discussed in this review. This review contains 12 figures, 5 tables, and 54 references. Key Words: carcinoid, duodenal carcinoma, duodenal adenocarcinoma, duodenal resection, duodenal tumors, neuroendocrine tumor, gastrointestinal stromal tumor, small bowel tumors

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