scholarly journals Protective effect of FK409, a nitric oxide donor, on ischemic acute renal failure in rat

1998 ◽  
Vol 76 ◽  
pp. 69
Author(s):  
Manabu Nishiura ◽  
Shogo Deguchi ◽  
Rumi Seo ◽  
Toshikazu Ogawa ◽  
Yasuo Matsumura
2000 ◽  
Vol 28 (3) ◽  
pp. 809-817 ◽  
Author(s):  
Hiroko Shimizu ◽  
Toru Takahashi ◽  
Tsutomu Suzuki ◽  
Akira Yamasaki ◽  
Tadao Fujiwara ◽  
...  

2000 ◽  
Vol 82 ◽  
pp. 70
Author(s):  
Junji Yamashita ◽  
Tosihiko Kuro ◽  
Makoto Itoh ◽  
Yutaka Kobayashi ◽  
Masanori Takaoka ◽  
...  

2008 ◽  
Vol 73 (3) ◽  
pp. 308-317 ◽  
Author(s):  
A. Satake ◽  
M. Takaoka ◽  
M. Nishikawa ◽  
M. Yuba ◽  
Y. Shibata ◽  
...  

1996 ◽  
Vol 270 (5) ◽  
pp. F784-F789
Author(s):  
Y. Wakabayashi ◽  
R. Kikawada

Because myoglobin is a potent inhibitor of nitric oxide (NO), we tested whether myoglobin infusion results in renal vasoconstriction and dysfunction, on which L-arginine, a source of NO, has a protective effect in sedated, nondehydrated, and nonacidotic rabbits. The infusion of myoglobin (375 mg/kg) resulted in a decrease in renal blood flow, an increase in renal vascular resistance, and a decrease in creatine clearance associated with a decrease in urinary excretory rate of nitrite/nitrate and guanosine 3',5'-cyclic monophosphate (cGMP). These values 1-2 h after the infusion were significantly different from baseline levels. Co-administration of L-arginine (150 mg/kg bolus followed by 150 mg.kg(-1).min(-1) reversed these changes significantly with attenuation of urinary excretory rate of nitrite/nitrate and cGMP. This study suggests that the myoglobin-induced renal vasoconstriction and dysfunction and protective effect of L-arginine on these outcomes could be mediated through the NO system.


2004 ◽  
Vol 44 (Supplement 1) ◽  
pp. S459-S461 ◽  
Author(s):  
Yujiro Shibata ◽  
Masanori Takaoka ◽  
Daisuke Maekawa ◽  
Chika Kuwahara ◽  
Yasuo Matsumura

2016 ◽  
Vol 5 (5) ◽  
pp. 408-412 ◽  
Author(s):  
Jing-Guang Liao ◽  
Min-Yan Li ◽  
Xiao-Hua Wang ◽  
Qiang Xie

2004 ◽  
Vol 44 (Supplement 1) ◽  
pp. S455-S458 ◽  
Author(s):  
Hayato Kurata ◽  
Masanori Takaoka ◽  
Yasuhiro Kubo ◽  
Tomoaki Katayama ◽  
Hidenobu Tsutsui ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document