Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)54597-x ◽

1991 ◽

Vol 266 (33) ◽

pp. 22479-22484 ◽

Author(s):

R.A. Anderson ◽

G.N. Sando

Keyword(s):

Cholesteryl Ester ◽

Cholesteryl Ester Hydrolase ◽

Cloning And Expression ◽

Acid Lipase ◽

Lysosomal Acid ◽

Ester Hydrolase ◽

Lysosomal Acid Lipase

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Human lysosomal acid lipase/cholesteryl ester hydrolase. Purification and properties of the form secreted by fibroblasts in microcarrier culture.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)95720-0 ◽

1985 ◽

Vol 260 (28) ◽

pp. 15186-15193 ◽

Author(s):

G N Sando ◽

L M Rosenbaum

Keyword(s):

Cholesteryl Ester ◽

Cholesteryl Ester Hydrolase ◽

Microcarrier Culture ◽

Acid Lipase ◽

Lysosomal Acid ◽

Ester Hydrolase ◽

Lysosomal Acid Lipase ◽

Purification And Properties

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Human lysosomal acid lipase/cholesteryl ester hydrolase and human gastric lipase: site-directed mutagenesis of Cys227 and Cys236 results in substrate-dependent reduction of enzymatic activity

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)37164-9 ◽

1997 ◽

Vol 38 (9) ◽

pp. 1896-1905

Author(s):

P Lohse ◽

P Lohse ◽

S Chahrokh-Zadeh ◽

D Seidel

Keyword(s):

Enzymatic Activity ◽

Cholesteryl Ester ◽

Cholesteryl Ester Hydrolase ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Acid Lipase ◽

Lysosomal Acid ◽

Ester Hydrolase ◽

Lysosomal Acid Lipase ◽

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Human lysosomal acid lipase/cholesteryl ester hydrolase and human gastric lipase: identification of the catalytically active serine, aspartic acid, and histidine residues

The Journal of Lipid Research ◽

10.1016/s0022-2275(20)37214-x ◽

1997 ◽

Vol 38 (5) ◽

pp. 892-903

Author(s):

P Lohse ◽

S Chahrokh-Zadeh ◽

P Lohse ◽

D Seidel

Keyword(s):

Cholesteryl Ester ◽

Aspartic Acid ◽

Cholesteryl Ester Hydrolase ◽

Acid Lipase ◽

Lysosomal Acid ◽

Histidine Residues ◽

Ester Hydrolase ◽

Lysosomal Acid Lipase ◽

Gastric Lipase ◽

Catalytically Active

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Properties of an Albumin Inhibiting Lysosomal Acid Cholesteryl Ester Hydrolase in Rat Liver.

Chemical and Pharmaceutical Bulletin ◽

10.1248/cpb.40.971 ◽

1992 ◽

Vol 40 (4) ◽

pp. 971-975

Author(s):

Mitsuo TANAKA ◽

Toshihiro IIO ◽

Toshikazu TABATA

Keyword(s):

Cholesteryl Ester ◽

Rat Liver ◽

Cholesteryl Ester Hydrolase ◽

Lysosomal Acid ◽

Ester Hydrolase

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Mutations at the lysosomal acid cholesteryl ester hydrolase gene locus in Wolman disease.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.91.7.2718 ◽

1994 ◽

Vol 91 (7) ◽

pp. 2718-2722 ◽

Author(s):

R. A. Anderson ◽

R. S. Byrum ◽

P. M. Coates ◽

G. N. Sando

Keyword(s):

Cholesteryl Ester ◽

Cholesteryl Ester Hydrolase ◽

Wolman Disease ◽

Lysosomal Acid ◽

Ester Hydrolase

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Prevalence of cholesteryl ester storage disease among hypercholesterolemic subjects and functional characterization of mutations in the lysosomal acid lipase gene

Molecular Genetics and Metabolism ◽

10.1016/j.ymgme.2017.11.008 ◽

2018 ◽

Vol 123 (2) ◽

pp. 169-176 ◽

Author(s):

Terje Vinje ◽

Lene Wierød ◽

Trond P. Leren ◽

Thea Bismo Strøm

Keyword(s):

Cholesteryl Ester ◽

Storage Disease ◽

Functional Characterization ◽

Acid Lipase ◽

Lipase Gene ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Hypercholesterolemic Subjects

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Lysosomal acid lipase deficiency: Wolman disease/cholesteryl ester storage disease

Atlas of Inherited Metabolic Diseases ◽

10.1201/9781315114033-94 ◽

2020 ◽

pp. 713-720

Author(s):

Christian Staufner

Keyword(s):

Cholesteryl Ester ◽

Storage Disease ◽

Acid Lipase ◽

Wolman Disease ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase ◽

Lysosomal Acid Lipase Deficiency

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Different missense mutations in histidine‐108 of lysosomal acid lipase cause cholesteryl ester storage disease in unrelated compound heterozygous and hemizygous individuals

Human Mutation ◽

10.1002/(sici)1098-1004(1998)12:1<44::aid-humu7>3.3.co;2-f ◽

1998 ◽

Vol 12 (1) ◽

pp. 44-51

Author(s):

Stefan Ries ◽

Christa Büchler ◽

Gisela Schindler ◽

Charalampos Aslanidis ◽

Detlev Ameis ◽

...

Keyword(s):

Cholesteryl Ester ◽

Storage Disease ◽

Compound Heterozygous ◽

Missense Mutations ◽

Acid Lipase ◽

Lysosomal Acid ◽

Lysosomal Acid Lipase

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Lysosomal acid lipase is the major acid retinyl ester hydrolase in cultured human hepatic stellate cells but not essential for retinyl ester degradation

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ◽

10.1016/j.bbalip.2020.158730 ◽

2020 ◽

Vol 1865 (8) ◽

pp. 158730

Author(s):

Carina Wagner ◽

Victoria Hois ◽

Laura Pajed ◽

Lisa-Maria Pusch ◽

Heimo Wolinski ◽

...

Keyword(s):

Hepatic Stellate Cells ◽

Stellate Cells ◽

Acid Lipase ◽

Lysosomal Acid ◽

Retinyl Ester ◽

Ester Hydrolase ◽

Lysosomal Acid Lipase ◽

Retinyl Ester Hydrolase ◽

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Cupric ion-dependent inhibition of lysosomal acid cholesteryl ester hydrolase in the presence of hydroxylamine

Lipids ◽

10.1007/bf02535292 ◽

1988 ◽

Vol 23 (2) ◽

pp. 126-130 ◽

Author(s):

Mitsuo Tanaka ◽

Toshihiro Iio ◽

Toshikazu Tabata

Keyword(s):

Cholesteryl Ester ◽

Cholesteryl Ester Hydrolase ◽

Lysosomal Acid ◽

Ester Hydrolase ◽

Dependent Inhibition

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