scholarly journals Site density of the sodium-calcium exchange carrier in reconstituted vesicles from bovine cardiac sarcolemma.

1988 ◽  
Vol 263 (5) ◽  
pp. 2309-2315
Author(s):  
J Cheon ◽  
J P Reeves
Keyword(s):  
Cardiac Sarcolemma ◽  
Site Density ◽  
Sodium Calcium ◽  
Calcium Exchange ◽  
Sodium Calcium Exchange

Cellular Regulation of Sodium-Calcium Exchange

2006 ◽  
Vol 976 (1) ◽  
pp. 214-223 ◽  
Author(s):  
MADALINA CONDRESCU ◽  
KWABENA OPUNI ◽  
BASIL M. HANTASH ◽  
JOHN P. REEVES
Keyword(s):  
Cellular Regulation ◽  
Sodium Calcium ◽  
Calcium Exchange ◽  
Sodium Calcium Exchange

Inhibition of sodium-calcium exchange in cardiac sarcolemmal membrane vesicles. 1. Mechanism of inhibition by amiloride analogs

Biochemistry ◽  
1988 ◽  
Vol 27 (7) ◽  
pp. 2403-2409 ◽  
Author(s):  
Robert S. Slaughter ◽  
Maria L. Garcia ◽  
Edward J. Cragoe ◽  
John P. Reeves ◽  
Gregory J. Kaczorowski
Keyword(s):  
Membrane Vesicles ◽  
Sarcolemmal Membrane ◽  
Sodium Calcium ◽  
Mechanism Of Inhibition ◽  
Calcium Exchange ◽  
Sodium Calcium Exchange ◽  
Amiloride Analogs

Potassium-Calcium and Sodium-Calcium Exchange on Kaolinite and Kaolinitic Soils

1988 ◽  
Vol 52 (5) ◽  
pp. 1259-1264 ◽  
Author(s):  
G. J. Levy ◽  
H. v. H. van der Watt ◽  
I. Shainberg ◽  
H. M. du Plessis
Keyword(s):  
Sodium Calcium ◽  
Calcium Exchange ◽  
Sodium Calcium Exchange

Inhibitors of sodium-calcium exchange: identification and development of probes of transport activity

1989 ◽  
Vol 988 (2) ◽  
pp. 287-302 ◽  
Author(s):  
Gregory J. Kaczorowski ◽  
Robert S. Slaughter ◽  
V. Frank King ◽  
María L. Garcia
Keyword(s):  
Transport Activity ◽  
Sodium Calcium ◽  
Calcium Exchange ◽  
Sodium Calcium Exchange

Lysophosphatidylcholine and sodium-calcium exchange in cardiac sarcolemma: comparison with ischemia

1991 ◽  
Vol 260 (3) ◽  
pp. C433-C438 ◽  
Author(s):  
M. M. Bersohn ◽  
K. D. Philipson ◽  
R. S. Weiss
Keyword(s):  
Phospholipase A2 ◽  
Phospholipid Composition ◽  
Maximum Velocity ◽  
Passive Permeability ◽  
Cardiac Sarcolemma ◽  
Sodium Calcium ◽  
Calcium Exchange ◽  
Sarcolemmal Vesicles ◽  
In Vitro Treatment

Lysophosphoglyceride accumulation in ischemic myocardium has been hypothesized to be a mechanism for altered sarcolemmal properties that underlie electrophysiological changes and Ca2+ accumulation in ischemia. We find that in vitro application of lysophosphatidylcholine to normal canine sarcolemmal vesicles at a concentration of 0.3 mumol/mg sarcolemmal protein inhibits Na(+)-Ca2+ exchange. Both maximum velocity (Vmax) for Ca2+ transport and Ca2+ affinity are reduced by lysophosphatidylcholine, whereas in ischemia only Vmax is reduced [M. M. Bersohn, K. D. Philipson, and J. Y. Fukushima. Am. J. Physiol. 242 (Cell Physiol. 11): C288-C295, 1982]. This amount of lysophosphatidylcholine does not affect sarcolemmal passive permeability to either Ca2+ or Na+. Treatment of sarcolemma with phospholipase A2 sufficient to inhibit Na(+)-Ca2+ exchange velocity by 50% causes large increases in sarcolemmal lysophosphatidylcholine and lysophosphatidylethanolamine. On the other hand, 1 h of ischemia in rabbit hearts does not affect sarcolemmal phospholipid composition. Thus, although in vitro treatment with lysophosphatidylcholine or phospholipase A2 has profound effects on sarcolemmal properties, sarcolemmal accumulation of lysophosphatidylcholine cannot account for the effects of ischemia as measured in highly purified sarcolemmal vesicles from ischemic hearts.

scholarly journals Inhibition of reverse‐mode sodium‐calcium exchange by the anti‐anginal agent ranolazine.

2010 ◽  
Vol 24 (S1) ◽  
Author(s):  
Daniel Soliman ◽  
Liango Wang ◽  
Kevin SC Hamming ◽  
Laura C Matemisz ◽  
Alexander S Clanachan ◽  
...  
Keyword(s):  
Reverse Mode ◽  
Sodium Calcium ◽  
Calcium Exchange ◽  
Sodium Calcium Exchange
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