scholarly journals GROWTH INHIBITION BY ANALOGUES OF PANTOTHENIC ACID. PANTOTHENYL ALCOHOL AND RELATED COMPOUNDS

1945 ◽  
Vol 158 (3) ◽  
pp. 551-559
Author(s):  
Esmond E. Snell ◽  
William Shive
1995 ◽  
Vol 7 (1) ◽  
pp. 46-49 ◽  
Author(s):  
King-Thom Chung ◽  
Guojing Zhao ◽  
Edward Stevens ◽  
Bill A. Simco ◽  
C. I. Wei

1965 ◽  
Vol 13 (2) ◽  
pp. 180-188 ◽  
Author(s):  
Masao Shimizu ◽  
Genkichi Ohta ◽  
Osamu Nagase ◽  
Seizaburo Okada ◽  
Yasuhiro Hosokawa

1993 ◽  
Vol 57 (10) ◽  
pp. 1766-1767 ◽  
Author(s):  
Kazuhiko Matsuda ◽  
Hideyoshi Toyoda ◽  
Kanako Yokoyama ◽  
Keiko Wakita ◽  
Hitomi Nishio ◽  
...  

1996 ◽  
Vol 43 (2) ◽  
pp. 407-410 ◽  
Author(s):  
V S Slyshenkov ◽  
M Rakowska ◽  
L Wojtczak

Preincubation of Ehrlich ascites tumour cells with millimolar concentrations of pantothenic acid, pantothenol or pantethine, but not with homopantothenic acid, at 22 degrees C or 32 degrees C, but not at 0 degrees C, makes the plasma membrane more resistant to the damaging effect of submillimolar concentrations of digitonin. It is proposed that this increased resistance is due to the increased rate of cholesterol biosynthesis. In fact, incorporation of [14C]acetate into cholesterol is by 45% increased in the cells preincubated with pantothenic acid; this probably reflects elevation of the content of CoA in such cells [Slyshenkov, V.S., Rakowska, M., Moiseenok, A.G. & Wojtczak, L. (1995) Free Radical Biol. Med. 19, 767-772].


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