The reserve albumin binding capacity as a criterion for exchange transfusion

1965 ◽  
Vol 67 (5) ◽  
pp. 1042-1044
Author(s):  
William J. Waters ◽  
Eva G. Porter
Keyword(s):  
Exchange Transfusion ◽  
Binding Capacity ◽  
Albumin Binding ◽  
Reserve Albumin

INDICATIONS FOR EXCHANGE TRANSFUSION BASED UPON THE ROLE OF ALBUMIN IN THE TREATMENT OF HEMOLYTIC DISEASE OF THE NEWBORN

PEDIATRICS ◽  
1964 ◽  
Vol 33 (5) ◽  
pp. 749-757
Author(s):  
William J. Waters ◽  
Eva Porter
Keyword(s):  
Exchange Transfusion ◽  
Serum Bilirubin ◽  
Binding Capacity ◽  
Hemoglobin Concentration ◽  
Hemolytic Disease ◽  
History Of ◽  
Unnecessary Procedures ◽  
Previously Treated ◽  
Reserve Albumin

Maternal titer, history of previously treated sibling, positive Coombs, prematurity, cord serum bilirubin, and hemoglobin concentration do not by themselves indicate the need for immediate exchange transfusion in an infant who shows no signs of disease. The measurement of the reserve albumin binding capacity is a useful aid in determining the need for exchange transfusion in preventing bilirubin encephalopathy. A delay in treatment of infants who have an adequate reserve binding capacity does not increase the need for re-exchange and avoids unnecessary procedures. The rate of re-exchange among infants receiving added albumin and managed according to the criteria outlined was lower than in the conventionally treated series.

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