Treatment of amœbic dysentery by injections of total ipecacuanha

Author(s):  
F. Roux
Keyword(s):  
1930 ◽  
Vol 2 (25) ◽  
pp. 823-823 ◽  
Author(s):  
Harold Crawford ◽  
Noel M. Gutteridge
Keyword(s):  

1926 ◽  
Vol 22 (5-6) ◽  
pp. 496-504
Author(s):  
Р. Mühlens

It is with the greatest joy that I go to meet the proposal of prof. Aristovsky to write an article on the treatment of amoebic dysentery for the anniversary issue in honor of my highly esteemed friend, Professor Gruzdev. I remember with gratitude during these hours that comradely-friendly welcome which I, together with the expedition of the German Red Cross, found in 1921-22. it was in the circle of persons of the Medical Faculty of Kazan University, grouped around prof. Gruzdev.


Parasitology ◽  
1931 ◽  
Vol 23 (1) ◽  
pp. 1-72 ◽  
Author(s):  
Clifford Dobell

Nine attempts to infect kittens directly with E. histolytica macacorurn by means of amoebae (per anum) or cysts (per os) in the faeces of 2 M. sinicus (Polo and Susanna) and 1 M. rhesus (Jacko), were wholly unsuccessful. Four similar experiments with cysts (per os) from another M. sinicus (Bonar) gave 2 positive (Kittens 28 and 31) and 2 negative results.Attempts to transmit strains of E. histolytica macacorum from one species of Macacus to another have been uniformly successful.A strain (D.) of E. histolytica, derived from a man suffering from acute amoebic dysentery, has been cultivated in vitro continuously for 5½ years.(i) The fact has been confirmed that strains of E. histolytica which, when newly isolated, are infective for kittens, may lose this infectivity after continued cultivation in vitro.


Parasitology ◽  
1929 ◽  
Vol 21 (4) ◽  
pp. 446-468 ◽  
Author(s):  
Clifford Dobell ◽  
Ann Bishop

Five tame monkeys (3 Macacus sinicus and 2 M. rhesus) have been treated with emetine bismuthous iodide per os, in order to study the effects of the alkaloid upon their intestinal amoebae (and other protozoa).These monkeys were originally infected with Entamoeba histolytica (large and small strains), Entamoeba coli, Endolimax nana, Enteromonas (= Tricercomonas), and Giardia. Treatment with emetine ultimately eradicated the E. histolytica infections from four out of five animals, but did not remove any of their other intestinal protozoa.It has been found necessary to administer 60 mg. of emetine bismuthous iodide daily for about a week to a macaque weighing about 5 kg. in order to eradicate an infection with E. histolytica. Such dosage was toxic to four of the five monkeys used.The general conclusion drawn is that emetine affects the various intestinal protozoa of M. sinicus and M. rhesus exactly as it does the comparable species in man; and it is suggested that macaques can therefore be utilized—if similar methods be employed—in place of men in future chemotherapeutic experiments directed towards the discovery of remedies for human amoebic dysentery.


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