A general route for the preparation of polymer-supported N-tosyl aminoalcohols and their use as chiral auxiliaries

2001 ◽  
Vol 42 (9) ◽  
pp. 1673-1675 ◽  
Author(s):  
Belén Altava ◽  
M.Isabel Burguete ◽  
Manuel Collado ◽  
Eduardo Garcı́a-Verdugo ◽  
Santiago V Luis ◽  
...  
Keyword(s):  
Chiral Auxiliaries ◽  
Polymer Supported

scholarly journals Chiral Auxiliaries in Polymer-Supported Organic Synthesis

ChemInform ◽  
2004 ◽  
Vol 35 (24) ◽  
Author(s):  
Cecilia Wan Ying Chung ◽  
Patrick H. Toy
Keyword(s):  
Organic Synthesis ◽  
Chiral Auxiliaries ◽  
Polymer Supported

scholarly journals Non-cross-linked polystyrene-supported 2-imidazolidinone chiral auxiliary: synthesis and application in asymmetric alkylation reactions

2013 ◽  
Vol 9 ◽  
pp. 2113-2119 ◽  
Author(s):  
Quynh Pham Bao Nguyen ◽  
Taek Hyeon Kim
Keyword(s):  
Carboxylic Acids ◽  
Chiral Auxiliary ◽  
Chiral Auxiliaries ◽  
Soluble Polymer ◽  
Asymmetric Alkylation ◽  
Polymer Supported ◽  
Alkylation Reactions

Asymmetric alkylation reactions using non-cross-linked polystyrene (NCPS)-supported 2-imidazolidinone chiral auxiliaries were successfully investigated with excellent diastereocontrol (>99% de). The recovery and the recycling of this soluble polymer-supported chiral auxiliary were achieved in order to produce highly optical pure carboxylic acids.

scholarly journals Chiral auxiliaries in polymer-supported organic synthesis

2004 ◽  
Vol 15 (3) ◽  
pp. 387-399 ◽  
Author(s):  
Cecilia Wan Ying Chung ◽  
Patrick H Toy
Keyword(s):  
Organic Synthesis ◽  
Chiral Auxiliaries ◽  
Polymer Supported

Synthesis of Axially Chiral 2,2’-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution

2020 ◽  
Author(s):  
Ziqing Zuo ◽  
Raphael Kim ◽  
Donald Watson
Keyword(s):  
Optical Resolution ◽  
Chiral Ligands ◽  
Chiral Auxiliaries ◽  
Axially Chiral ◽  
Ullmann Coupling

<div><p>We report an asymmetric Ullmann-type homocoupling of <i>ortho-</i>(iodo)arylphosphine oxides and <i>ortho</i>-(iodo)arylphosphonates that results in highly enantioenriched axially chiral bisphosphine oxides and bisphosphonates in good yields and excellent enantioselectivities. These products are readily converted to enantioenriched biaryl bisphosphines without need for chiral auxiliaries or optical resolution. This process provides a straightforward and practical route for the development of previously uninvestigated atroposelective biaryl bisphosphine ligands.</p></div>

Recent Application of Polystyrene-supported Triphenylphosphine in Solid-Phase Organic Synthesis

2019 ◽  
Vol 23 (6) ◽  
pp. 643-678
Author(s):  
Lalthazuala Rokhum ◽  
Ghanashyam Bez
Keyword(s):  
Organic Synthesis ◽  
Combinatorial Chemistry ◽  
Solid Phase ◽  
Recent Application ◽  
Organic Transformations ◽  
Solid Phase Organic Synthesis ◽  
Wide Range ◽  
Fast Development ◽  
Polymer Supported

Recent years have witnessed a fast development of solid phase synthetic pathways, a variety of solid-supported reagent and its applications in diverse synthetic strategies and pharmaceutical applicability’s. Polymer-supported triphenylphosphine is getting a lot of applications owing to the speed and simplicity in the process. Furthermore, ease of recyclability and reuse of polymer-supported triphenylphosphine added its advantages. This review covers a wide range of useful organic transformations which are accomplished using cross-linked polystyrene-supported triphenylphosphine with the aim of giving renewed interest in the field of organic and medicinal-combinatorial chemistry.

An Efficient Synthesis of 2-Substituted Quinazolin-4(3H)-ones by Using Recyclable Wang Resin Supported Sulfonic Acid Catalyst

2020 ◽  
Vol 17 ◽  
Author(s):  
Kalyani K. ◽  
Srinivasa Reddy Kallam
Keyword(s):  
Sulfonic Acid ◽  
Functional Group ◽  
Acid Catalyst ◽  
Sulphonic Acid ◽  
Isatoic Anhydride ◽  
Efficient Synthesis ◽  
Wang Resin ◽  
Polymer Supported ◽  
High Yields

Abstract:: An efficient synthesis of 2-substituted Quinazolin-4(3H)-ones has been developed from isatoic anhydride with various amidoximes by using recyclable polymer supported sulphonic acid catalyst. Excellent functional group compatibil-ity and high yields are the important features of this protocol.

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